Results 151 to 160 of about 284,658 (331)

Designing and Testing the Structural Model of Online Games Addiction Based on Brain-Behavioral Systems: The Mediating Role of Cognitive Fusion and Experiential Avoidance

open access: yesروانشناسی و روانپزشکی شناخت
Introduction: Online games addiction is a growing concern which the prevalence is estimated at 1.2 to 8.5 percent among teenagers and young adults.
Mohammad Herangza   +3 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Mobitz II atrioventricular block and CPAP response in a patient with severe obstructive sleep apnea, a case report

open access: yesSleep Science and Practice
Background At any stage during the sleep cycle, cardiac arrhythmia can happen. While many of these arrhythmias are benign, some of them are dangerous and may result in cardiovascular events that could be life-threatening.
Farkhondeh Nikkhah   +2 more
doaj   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Repetitive Transcranial Magnetic Stimulation (rTMS) as a Promising Treatment for Craving in Stimulant Drugs and Behavioral Addiction: A Meta-Analysis. [PDF]

open access: yesJ Clin Med, 2022
Gay A   +10 more
europepmc   +1 more source

Rats classified as low or high cocaine locomotor responders: A unique model involving striatal dopamine transporters that predicts cocaine addiction-like behaviors

open access: green, 2013
Dorothy J. Yamamoto   +9 more
openalex   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy