Results 71 to 80 of about 103,401 (257)

Effect of exercise intervention on internet behavioral addictions: a systematic review of systematic reviews

open access: yesZhongguo kangfu lilun yu shijian
Objective To systematically review the evidence from systematic reviews on the effect of exercise on internet behavioral addictions. Methods Systematic reviews on exercise for internet behavioral addictions were searched in Web of Science, Scopus, EBSCO,
YE Lü, CHANG Jing, LING Hairun
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Behavioral Addiction versus Substance Addiction: Correspondence of Psychiatric and Psychological Views

open access: yesInternational Journal of Preventive Medicine, 2012
Introduction: Behavioral science experts believe that all entities capable of stimulating a person can be addictive; and whenever a habit changes into an obligation, it can be considered as an addiction.
Seyyed Salman Alavi   +5 more
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Demographic characteristics in unplanned versus planned suicide attempts: a comparative study from Yazd, Iran

open access: yesBMC Psychology
Introduction Suicide is a significant global health concern, particularly in Iran, where the rate of suicide attempts has remained high. Understanding the demographic differences between unplanned and planned suicide attempts is essential for tailoring ...
Kamyab Peyman   +6 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Social network characteristics of COVID-19 vaccination and preventive health behaviors: Cross-sectional findings from the US northeast during the early COVID-19 pandemic

open access: yesVaccine: X
Background: The link between individuals’ vaccine attitudes and their social networks has been widely studied, but less is known about how these networks impact broader health behaviors like precautionary measures during the COVID-19 pandemic.
Aditya S. Khanna   +3 more
doaj   +1 more source

Romantic love v.s. drug addiction may inspire a new treatment for addiction

open access: yesFrontiers in Psychology, 2016
Drug addiction is a complex neurological dysfunction induced by recurring drug intoxication. Strategies to prevent and treat drug addiction constitute a topic of research interest.
Zhiling Zou   +7 more
doaj   +1 more source

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