Results 71 to 80 of about 103,587 (257)

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Behavioral Addiction versus Substance Addiction: Correspondence of Psychiatric and Psychological Views

open access: yesInternational Journal of Preventive Medicine, 2012
Introduction: Behavioral science experts believe that all entities capable of stimulating a person can be addictive; and whenever a habit changes into an obligation, it can be considered as an addiction.
Seyyed Salman Alavi   +5 more
doaj  

Effect of exercise intervention on internet behavioral addictions: a systematic review of systematic reviews

open access: yesZhongguo kangfu lilun yu shijian
Objective To systematically review the evidence from systematic reviews on the effect of exercise on internet behavioral addictions. Methods Systematic reviews on exercise for internet behavioral addictions were searched in Web of Science, Scopus, EBSCO,
YE Lü, CHANG Jing, LING Hairun
doaj   +1 more source

Food addiction in behavioral addictions: a network approach

open access: yesFrontiers in Psychology
Background/aims The comorbidity of mental disorders is a well-documented phenomenon. However, the co-occurrence of and underlying mechanisms of food addiction (FA) and behavioral addictions (BAs) have been scarcely investigated. Therefore, the aims of this study were as follows: (a) to perform a network analysis
Gaspar-Pérez, Anahí   +11 more
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Demographic characteristics in unplanned versus planned suicide attempts: a comparative study from Yazd, Iran

open access: yesBMC Psychology
Introduction Suicide is a significant global health concern, particularly in Iran, where the rate of suicide attempts has remained high. Understanding the demographic differences between unplanned and planned suicide attempts is essential for tailoring ...
Kamyab Peyman   +6 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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