Results 71 to 80 of about 362,039 (290)
The ecology of exercise: mechanisms underlying Individual variation in behavior, activity, and performance: an introduction to symposium [PDF]
Wild animals often engage in intense physical activity while performing tasks vital for their survival and reproduction associated with foraging, avoiding predators, fighting, providing parental care, and migrating.
Auer +116 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Physical and psychological health of medical students: A structural equation modeling approach
Objective: This study aims to expand the application of behavioral immune system theory during public health emergencies and explore potential strategies to avoid “health poverty” in the post-pandemic era, focusing on Chinese medical students. Methods: A
Chengcheng Li +5 more
doaj +1 more source
Paternal early experiences influence infant development through non-social mechanisms in Rhesus Macaques. [PDF]
BackgroundEarly experiences influence the developing organism, with lifelong and potentially adaptive consequences. It has recently become clear that the effects of early experiences are not limited to the exposed generation, but can influence ...
Capitanio, John P, Kinnally, Erin L
core +3 more sources
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
During outbreaks such as severe acute respiratory syndrome and COVID 19, many Emergency Departments across the world had a reduction in the general attendance, including the attendance of more serious and critical diagnoses.
Fatimah Lateef
doaj +1 more source
Background and purpose: Behavioral immune system is a cluster of psychological mechanisms enabling detection and avoidance of pathogens in one’s immediate environment. Its presumed activation has been implicated in myriads of psychological phenomena, stemming from pathogen related disgust to more complex behaviors, such as mate choice and xenophobic ...
Ivana Hromatko, Andreja Bubić
openaire +2 more sources
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Neuron-Specific HuR-Deficient Mice Spontaneously Develop Motor Neuron Disease [PDF]
Human Ag R (HuR) is an RNA binding protein in the ELAVL protein family. To study the neuron-specific function of HuR, we generated inducible, neuron-specific HuR-deficient mice of both sexes.
Bai, Ying +10 more
core +1 more source

