Results 71 to 80 of about 3,282,089 (253)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Other title: 2012 DMHAS Behavioral Health Recovery Program provider manual
"Clinical Recovery Supports-Basic Recovery Supports."; Previously published: Provider manual / State of Connecticut, Department of Mental Health and Addiction Services, General Assistance Behavioral Health Program. [Hartford : Connecticut Dept. of Mental
Behavioral Health Recovery Program (Conn.)
core +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Behavioral Models of I/O Ports from Measured Transient Waveforms [PDF]
This paper addresses the development of accurate and efficient behavioral models of digital integrated circuit ports from measured transient responses.
Stievano, Igor Simone +2 more
core +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
A behavioral modeling approach to bicycle level of service
Bicycle level of service (LOS) measures are essential tools for transportation agencies to monitor and prioritize improvements to infrastructure for cyclists.
Griswold, Julia B. +4 more
core +1 more source
Preliminary Research on Verification and Validation for CGF Behavioral Modeling
: Building computer generated force model is a very important job in combat simulation. Its core content is modeling of complicated human behavior, including cognition behavioral modeling and physical behavioral modeling.
Qi, Zhang +3 more
core +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source

