Results 61 to 70 of about 872,884 (298)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Pupil-linked phasic arousal predicts a reduction of choice bias across species and decision domains

open access: yeseLife, 2020
Decisions are often made by accumulating ambiguous evidence over time. The brain’s arousal systems are activated during such decisions. In previous work in humans, we found that evoked responses of arousal systems during decisions are reported by rapid ...
Jan Willem de Gee   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The role of effective communication and trustworthiness in determining guests’ loyalty [PDF]

open access: yes, 2018
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.This study investigates the role of trustworthiness and effective communication in the development of ...
Fazal-e-Hasan, Syed Muhammad   +4 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Non-Linear Behavioral Modeling for DC-DC Converters and Dynamic Analysis of Distributed Energy Systems

open access: yesEnergies, 2017
In modern distributed energy systems (DES), focus is shifting from the conventional centralized approach towards distributed architectures. However, modeling and analysis of these systems is more complex, as it involves the interface of multiple energy ...
Xiancheng Zheng   +4 more
doaj   +1 more source

State maps for linear systems

open access: yes, 1997
Modeling of physical systems consists of writing the equations describing a phenomenon and yields as a result a set of differential-algebraic equations.
Rapisarda, Paolo, Willems, Jan C.
core   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Behavioral Models for Lithium Batteries Based on Genetic Programming

open access: yesIEEE Access
This paper proposes a novel methodology based on the Genetic Programming (GP) to derive behavioral models describing the transient evolution of the terminal voltage of a battery. These models analytically relate the battery voltage to its state of charge,
Giulia Di Capua   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy