Results 111 to 120 of about 623,756 (293)

Seeing Voices: Potential Neuroscience Contributions to a Reconstruction of Legal Insanity [PDF]

, 2016
Part I of this Article explains the insanity defense in the United States. Next, Part II discusses some of the brain-based research about mental illness, focusing on schizophrenia research.
Moriarty, Jane Campbell
core   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Transformation of spatial representations along hippocampal circuits

iScience
Summary: The hippocampus is thought to provide the brain with a cognitive map of the external world by processing various types of spatial information.
Bérénice Gandit, Lorenzo Posani, Chun-Lei Zhang, Soham Saha, Cantin Ortiz, Manuela Allegra, Christoph Schmidt-Hieber   +6 more
doaj   +1 more source

Transcriptional diversity of the oxytocin receptor in prairie voles: mechanistic implications for behavioral neuroscience and maternal physiology. [PDF]

Front Genet, 2023
Danoff JS, Page EA, Perkeybile AM, Kenkel WM, Yee JR, Ferris CF, Carter CS, Connelly JJ.   +7 more
europepmc   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Neural markers of social dominance: A female-focused perspective

iScience
Summary: Social interactions are fundamental to human life, with social dominance being a key factor in these interactions. Previous studies have shown that dominant males are faster in decision-making tasks compared to non-dominant ones, even in the ...
Wei-Hsiang Lin, Janir Ramos da Cruz, Carmen Sandi, Michael H. Herzog   +3 more
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

PiRATeMC: A highly flexible, scalable, and low-cost system for obtaining high quality video recordings for behavioral neuroscience. [PDF]

Addict Neurosci, 2023
Centanni SW, Smith ACW.
europepmc   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Kv2 channels do not function as canonical delayed rectifiers in spinal motoneurons

iScience
Summary: The increased muscular force output required for some behaviors is achieved via amplification of motoneuron output via cholinergic C-bouton synapses.
Calvin C. Smith, Filipe Nascimento, M. Görkem Özyurt, Marco Beato, Robert M. Brownstone   +4 more
doaj   +1 more source