Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Effects of Enamel Paint on the Behavior and Survival of the Periodical Cicada, \u3ci\u3eMagicicada Septendecim\u3c/i\u3e (Homoptera) and the Lesser Migratory Grasshopper, \u3ci\u3eMelanoplus Sanguinipes (Orthoptera). [PDF]
, 2018 We present information compiled from several studies on the effects of methods for marking individual arthropods on their longevity and behavior. Results from our own research on effects of enamel paint marking on two in- sect species, the periodical ...
Cooley, J. R +2 more
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Electronic Health Records in Behavioral Research
International Journal of Population Data Science, 2018 Medical records are a type of administrative record with rich potential for research of behavioral health and health policy. Developments in electronic health records (EHR) can increase access to data contained in medical records but also present some ...
John Loft, Diana Greene
doaj +1 more source
Behavioral technology and its application to fire toxicology research [PDF]
The application of behavioral technology to the toxicity testing of pyrolysis/combustion (P/C) products is discussed and two categories of behavioral tests commonly employed in fire toxicology programs are reviewed.
Russo, D. M.
core +1 more source
Learning and Production of Movement Sequences: Behavioral, Neurophysiological, and Modeling Perspectives [PDF]
, 2003 A growing wave of behavioral studies, using a wide variety of paradigms that were introduced or greatly refined in recent years, has generated a new wealth of parametric observations about serial order behavior.
Averbeck, Bruno +4 more
core +1 more source
Opening the Black Box: Explaining the Process of Basing a Health Recommender System on the I-Change Behavioral Change Model [PDF]
, 2019 Recommender systems are gaining traction in healthcare because they can tailor recommendations based on users' feedback concerning their appreciation of previous health-related messages. However, recommender systems are often not grounded in behavioral
Amaya Rodríguez, Claudio Antonio +9 more
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Ethics and the moral life [PDF]
, 1980 The article summarizes recent social scientific studies of the moral life, and pedogogies for moral education, in their relation to normative inquiry (ethics).
Hoehn, Richard A.
core +1 more source
Frontotemporal dementia: the impact of patient behavioral symptoms on the physical and mental health of family caregivers. [PDF]
, 2012 BackgroundProviding informal support to someone with frontotemporal dementia (FTD) could be very stressful. Clarifying the relationship between patient behavioral problems and caregiver health could spur future research on effective symptom management ...
Wallhagen, Margaret I, Wong, Cindy C
core +3 more sources