Results 61 to 70 of about 1,165,410 (265)

Interpreting Likert type, summated, unidimensional, and attitudinal scales: I neither agree nor disagree, Likert or not

Advancements in Agricultural Development
This paper provides a rationale and convention for discussing the true limits and interpretation of data collected using unidimensional, summated, Likert-type, and attitudinal scales used in research investigating human behavior, sociology, education ...
James R. Lindner, Nicholas Lindner
doaj   +1 more source

Artificial research participants in behavioral science [PDF]

Journal of Ethics in Entrepreneurship and Technology
PurposeThe potential for large language models (LLMs) to improve behavioral science research has generated significant discussion. But, the specific role that LLMs should serve in behavioral research, especially in terms of simulating human participants,
Vincent A. Medina, Mrityunjay Mohan
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Electronic Health Records in Behavioral Research

International Journal of Population Data Science, 2018
Medical records are a type of administrative record with rich potential for research of behavioral health and health policy. Developments in electronic health records (EHR) can increase access to data contained in medical records but also present some ...
John Loft, Diana Greene
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Developing optimized physical activity interventions for drug-resistant epilepsy: Challenges and lessons learned from a remote exercise intervention pilot trial

Epilepsy & Behavior Reports
People with epilepsy (PWE) stand to benefit significantly from increasing their physical activity, but promotion of physical activity is difficult in any population; a challenge compounded by the unique barriers encountered by PWE, especially those with ...
Halley B. Alexander, Heidi M. Munger Clary, Hossam A. Shaltout, Nathan B. Fountain, Pamela Duncan, Peter Brubaker, Jason Fanning   +6 more
doaj   +1 more source

Decreasing Nicotine Content Reduces Subjective and Physiological Effects of Smoking

Tobacco Use Insights, 2012
Objective Assessment of the subjective and physiological effects of smoking cigarettes with different machine-smoked nicotine yields. Methods Eight volunteers rated the characteristics of cigarettes with varying levels of nicotine (Quest ® ).
David M. Penetar, Kimberly P. Lindsey, Erica N. Peters, Trisha M. Juliano, Scott E. Lukas   +4 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source