Results 71 to 80 of about 1,167,880 (265)

Decreasing Nicotine Content Reduces Subjective and Physiological Effects of Smoking

Tobacco Use Insights, 2012
Objective Assessment of the subjective and physiological effects of smoking cigarettes with different machine-smoked nicotine yields. Methods Eight volunteers rated the characteristics of cigarettes with varying levels of nicotine (Quest ® ).
David M. Penetar, Kimberly P. Lindsey, Erica N. Peters, Trisha M. Juliano, Scott E. Lukas   +4 more
doaj   +1 more source

Exploring the Perspectives of Lung Cancer Chemotherapy Patients on Self-Management: A Qualitative Interview Study Using the COM-B Model

Patient Preference and Adherence
Ruimei Jia,1,* Nina Xie,1,* Yue Li,2 Yu Zhang2 1School of Nursing, Shaanxi University of Chinese Medicine, Xianyang, People’s Republic of China; 2Department of Internal Medicine, Shaanxi Provincial Cancer Hospital, Xi’an, People’s ...
Jia R, Xie N, Li Y, Zhang Y
doaj  

Polypharmacy and pharmacogenomics in high-acuity behavioral health care for autism spectrum disorder: a retrospective study

Child and Adolescent Psychiatry and Mental Health
Background This study evaluated pharmacogenomic (PGx) testing in children and adolescents with autism spectrum disorder (ASD). ASD frequently presents with co-occurring depression and anxiety.
Sheldon R. Garrison, Sophie A. Schweinert, Matthew W. Boyer, Maharaj Singh, Sreya Vadapalli, Jeffery M. Engelmann, Rachel A. Schwartz, Madeline M. Hartig   +7 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Percepción de la motivación de los directivos intermedios en tres hospitales de la Región del Maule, Chile Motivation perception measurement of intermediate directors in three complex hospitals of the Region of the Maule, Chile

Salud Pública de México, 2009
OBJETIVO: En este trabajo se diseña un cuestionario y se cuantifican las percepciones de motivación-desmotivación de los jefes intermedios de tres hospitales de la Región del Maule, Chile.
Miguel Alejandro Bustamante-Ubilla, María Carolina del Río-Rivero, Germán Enrique Lobos-Andrade, Patricia Isabel Villarreal-Navarrete   +3 more
doaj  

Bridging psychiatry and rare genetic diseases: a scoping review of therapeutic strategies and diagnostic delay paired with healthcare economic burden analysis

Orphanet Journal of Rare Diseases
Rare genetic diseases (RDs) with primary neuropsychiatric symptoms pose unique challenges for diagnosis and management. While the majority of these RDs have neuropsychiatric symptoms that are secondary to the RD, a subset presents with primary ...
Sheldon R. Garrison, Isaac J. Siegel, Christopher R. Takala, Sarah L. Vaithilingam, Gene W. Yang, Anthony W. Zoghbi, Madeline M. Hartig, Sreya Vadapalli, Margaret E. Anderson   +8 more
doaj   +1 more source

Clinical and theoretical issues in self-injurious behavior

Brazilian Journal of Psychiatry, 1999
This article presents an overview of pathological self-injurious behavior (SIB). Historical and cultural aspects, epidemiology, classification and clinical aspects and pathogenesis are described.
Jose A. Yaryura-Tobias, Maria C. Mancebo, Fugen A. Neziroglu   +2 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source