Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Cultures within a culture: the role of nationality and religion for environmentally significant behaviour in students living in university accommodation [PDF]
, 2011 Reducing global warming cannot be achieved through technological interventions alone; it requires a change in human behaviour. Households are a major contributor to carbon emissions, and thus play an integral part in strategies aiming at a more ...
Cooper, J., Huebner, G.M., Jones, K.
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Communications BiologyAvoidance, a hallmark of anxiety-related psychopathology, often comes at a cost; avoiding threat may forgo the possibility of a reward. Theories predict that optimal approach-avoidance arbitration depends on threat-induced psychophysiological states ...
Felix H. Klaassen +6 more
doaj +1 more source
The drivers of technology adoption on tobacco agribusiness in West Nusa Tenggara
AgrointekWest Nusa Tenggara (NTB) is the third-largest tobacco-producing province in Indonesia. However, the dynamics of tobacco production tend to decline, one of which is due to its productivity and land area, which also tends to stagnate.
Eka Nurjati +3 more
doaj +1 more source
Experimental and numerical study on the in-plane behaviour of a new long-span assembly composite floor system under lateral load [PDF]
, 2021 Zaihua Zhang +3 more
openalex +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Reactions to social videos in long-tailed macaques
Animal CognitionAnimals can obtain important social information by observing social interactions among conspecifics. Depending on the social content, such as familiarity with the conspecifics and the type of interaction, the receiver’s attention, and possibly also ...
Elisabeth H. M. Sterck +6 more
doaj +1 more source
Longitudinal influence of self-compassion and fears of compassion on prosocial and antisocial behaviour in sport: A conditional latent growth curve modelling analysis [PDF]
, 2023 Kirsten McEwan, Shuge Zhang
openalex +1 more source