Results 61 to 70 of about 722,698 (284)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Effects of Behavioural Biases on Investment Decisions: A Systematic and Meta-Analysis [PDF]
Management and Economics ReviewTraditional finance theories assume that investors behave rationally and make decisions based on complete information. However, empirical evidence indicates that investors are often influenced by behavioural biases that lead to deviations from rational ...
Louis TAKARUZA, Robert MWANYEPEDZA
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Optimistic and pessimistic biases: a primer for behavioural ecologists [PDF]
, 2016 To address the adaptive value of optimism/pessimism an operational definition is required. I define a behavioural decision as relatively optimistic if it is consistent with the animal having either, a higher expectation of reward, or a lower expectation ...
Bateson M
core +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
A systematic review of ordinary people, behavioural financial biases [PDF]
, 2020 ehavioural Finance and Behavioural Economics are jointly fastgrowing fields of research, which encompass both academicia and business. Therefore, the purpose of this paper is to study the biases in decision-making by ordinary investors, also ...
Bordonado-Bermejo, M.J. +5 more
core +1 more source
Behavioural Biases Scale for Retail Investors' Trading Behaviour
African Journal of Empirical ResearchThe purpose of this paper was to describe the development of a survey instrument designed to directly measure the effects of the underlying psychological constructs on the behaviour of retail-investors engaging in stock trading at the Dar es Salaam stock exchange.
openaire +3 more sources
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source