Results 31 to 40 of about 1,025,641 (274)

Significant determinants of mouse pain behaviour.

open access: yesPLoS ONE, 2014
Transgenic mouse behavioural analysis has furthered our understanding of the molecular and cellular mechanisms underlying damage sensing and pain. However, it is not unusual for conflicting data on the pain phenotypes of knockout mice to be generated by ...
Michael S Minett   +2 more
doaj   +1 more source

Executive functioning in Cornelia de Lange syndrome: domain asynchrony and age-related performance

open access: yesJournal of Neurodevelopmental Disorders, 2017
Background The aim of this study was to examine executive functioning in adolescents and adults with Cornelia de Lange syndrome (CdLS) to identify a syndrome and age-related profile of cognitive impairment.
Donna Reid   +4 more
doaj   +1 more source

Automated home-cage behavioural phenotyping of mice [PDF]

open access: yesNature Communications, 2010
Neurobehavioural analysis of mouse phenotypes requires the monitoring of mouse behaviour over long periods of time. In this study, we describe a trainable computer vision system enabling the automated analysis of complex mouse behaviours. We provide software and an extensive manually annotated video database used for training and testing the system ...
Hueihan, Jhuang   +7 more
openaire   +4 more sources

Behavioural phenotype of sensitisation at micro and macro level.

open access: yes, 2013
Behavioural phenotype of sensitisation at micro and macro level.
Nele Jacobs (35964)   +7 more
core   +1 more source

Host plant effects on the behavioural phenotype of a Chrysomelid

open access: yes, 2017
Müller T, Müller C. Host plant effects on the behavioural phenotype of a Chrysomelid. Ecological Entomology.
Müller, Thorben   +3 more
core   +1 more source

Neuropsychiatric manifestations in Cornelia de Lange syndrome

open access: yesEuropean Psychiatry, 2023
Introduction Cornelia De Lange syndrome (CdLS) is a dominant and rare genetically heterogeneous syndrome. It is characterized by a large phenotypical spectrum going from a classical to a non-classical form affecting multiple organ systems including ...
F. Majdoub   +11 more
doaj   +1 more source

Pharmacological manipulation of serotonin receptors during brain embryogenesis favours stress resiliency in female rats

open access: yesJournal of Biological Research, 2018
Manipulations of the serotonin transmission during early development induce long-lasting changes in the serotonergic circuitry throughout the brain. However, little is known on the developmental consequences in the female progeny.
Gianluca Lavanco   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Profiling the behavioural phenotype of genetic syndromes [PDF]

open access: yes, 2015
Background: Potocki-Lupski syndrome (PTLS) is caused by a duplication within 17p11.2. A deletion within this region is associated with Smith-Magenis syndrome (SMS).
Bissell, Stacey Louise
core   +5 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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