Results 31 to 40 of about 1,081 (250)
Speculating the architecture of nothingness through void operations
ARSNETThis speculative design study aims to construct the idea of nothingness as an active and generative element of architecture. Nothingness, understood as voids, empty, and negative spaces, can be reinterpreted as a productive condition that opens up new ...
Fatiharla Imanisahda, Yandi Andri Yatmo
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Wniknąć w nicość. Bernharda Weltego wykład o nadziei i rozpaczy [PDF]
Argument, 2013 The thought of Bernhard Welte, a philosopher of religion from Fribourg, many times touched upon the subject of nothingness. This article aims at presenting the function he ascribed to the idea of nothingness in the context of constitutive experience ...
Joachim PIECUCH
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Between being and nothingness: Sartre´s existential phenomenology of liberation
Veritas, 2003 O artigo tenta mostrar como a dialética sartreana do ser e do nada se afasta da concepção fundamental heideggeriana do Dasein enquanto ser-no-mundo, na medida em que seu modo de ser e autocompreensão existenciais conduzem-no em última análise à sua ...
Oliveira Junior, Nythamar Hilario Fernandes de
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Byt i nicość w myśli Mistrza Eckharta. Początki niemieckiej filozofii woli [PDF]
Argument, 2013 The article is devoted to Meister Eckhart’s interpretation of ontological structures of reality in which the concepts of being, nothingness, existence, and Godhead play an important role. The article discusses: 1.
Piotr AUGUSTYNIAK
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Labyrinth: An International Journal for Philosophy, Value Theory and Sociocultural Hermeneutics, 2019 Philosophical translation between "linguistic violence" and translative hermeneutics. Translational considerations from the perspective of the translation(s) of Jean-Paul Sartre's L'être et le néant The establishment of translatology as a scientific ...
Yvanka Raynova
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Heidegger, Nothingness, and Presence: Between Parmenides and Laozi
FilozofiaThis contribution reconsiders standard accounts of Heidegger’s concept of being as presence by tracing other moments revealed in his thinking of nothingness, emptiness, and the clearing in the context of his European and East Asian sources.
Eric S. Nelson
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