Results 101 to 110 of about 470,247 (283)

XeraBorg: Neural Control of Tail‐Flick Escape for Backward Propulsion in Cyborg Crayfish

open access: yesAdvanced Robotics Research, EarlyView.
This work presents the first controlled tail‐flick propulsion method for the cyborg Cherax quadricarinatus. Comprehensive experiments establish a foundational framework for using the crayfish's natural escape mechanism as a locomotion strategy, expanding its potential as an underwater and amphibious mobile robot.
H. Nhan Le   +7 more
wiley   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

open access: yesAdvanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao   +7 more
wiley   +1 more source

Applying Quadratic Scoring Rule transparently in multiple choice settings: A note [PDF]

open access: yes
The quadratic scoring rule (QSR) is often used to guarantee an incentive compatible elicitation of subjective probabilities over events. Experimentalists have regularly not been able to ensure that subjects fully comprehend the consequences of their ...
Hannes Koppel   +3 more
core  

BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu   +13 more
wiley   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

open access: yesAdvanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang   +11 more
wiley   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

open access: yesAdvanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann   +11 more
wiley   +1 more source

Bayesian Belief Network Model Quantification Using Distribution-Based Node Probability and Experienced Data Updates for Software Reliability Assessment

open access: yesIEEE Access, 2018
Since digital instrumentation and control systems are expected to play an essential role in safety systems in nuclear power plants (NPPs), the need to incorporate software failures into NPP probabilistic risk assessment has arisen.
Seung Jun Lee   +7 more
doaj   +1 more source

RATIO-SCALE ELICITATION OF DEGREES OF BELIEF [PDF]

open access: yes, 1988
Most research on rule-based inference under uncertainty has focused on the normative validity and efficiency of various belief-update algorithms. In this paper we shift the attention to the inputs of these algorithms, namely, to the degrees of beliefs ...
Schocken, Shimon
core   +2 more sources

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

open access: yesAdvanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan   +6 more
wiley   +1 more source

Barriers to accessing and using contraception in highland Guatemala: the development of a family planning self-efficacy scale

open access: yesOpen Access Journal of Contraception, 2016
Emma Richardson,1 Kenneth R Allison,1,2 Dionne Gesink,1 Albert Berry3 1Dalla Lana School of Public Health, University of Toronto, 2Public Health Ontario, 3Department of Economics, Munk Centre for International Studies, University of Toronto, Toronto, ON,
Richardson E   +3 more
doaj  

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