Results 71 to 80 of about 1,058,148 (324)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Students' conceptual understanding of limit of functions reviewed from mathematical beliefs

open access: yesJurnal Elemen
Conceptual understanding is a student’s cognitive structure characterised by the ability to transform and explain concepts in solving problems. Many students were unable to explain the concepts and the relationships between concepts in solving the limit
Usman, Aiyub, M. Hasbi
doaj   +1 more source

Belief Function Robustness in Estimation [PDF]

open access: yes, 2012
We consider the case in which the available knowledge does not allow to specify a precise probabilistic model for the prior and/or likelihood in statistical estimation. We assume that this imprecision can be represented by belief functions. Thus, we exploit the mathematical structure of belief functions and their equivalent representation in terms of ...
openaire   +1 more source

On the Orthogonal Projection of a Belief Function [PDF]

open access: yes, 2007
In this paper we study a new probability associated with any given belief function b, i.e. the orthogonal projection π[b] of b onto the probability simplex P. We provide an interpretation of π[b] in terms of a redistribution process in which the mass of each focal element is equally distributed among its subsets, establishing an interesting analogy ...
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Believing Selves and Cognitive Dissonance: Connecting Individual and Society via “Belief”

open access: yesReligions, 2016
“Belief” as an analytical tool and critical category of investigation for the study of religion has been a resurging topic of interest. This article discusses the problems of language and practice in the discussion of “belief” and proceeds to map a few ...
Bosco B. Bae
doaj   +1 more source

Distributed combination of belief functions

open access: yesInformation Fusion, 2021
Abstract We consider the problem of combining belief functions in a situation where pieces of evidence are held by agents at the node of a communication network, and each agent can only exchange information with its neighbors. Using the concept of weight of evidence, we propose distributed implementations of Dempster’s rule and the cautious rule ...
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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