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Defining Phytochemical Metabolomes of Somatic Hybrids <i>Gentiana cruciata</i> L. (+) <i>G. tibetica</i> King ex Hook.f. (Gentianaceae) Using UHPLC-DAD-ESI-MS<sup>3</sup> Analysis in Comparison to the Parental Species. [PDF]
MoleculesObrębski M +3 more
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DESIGN AND DEVELOPMENT OF A SUSTAINABLE MANUFACTURING PROCESS FOR THE PREPARATION OF ALBUMIN-BASED NANOMEDICINE ABLE TO CARRY LIPOPHILIC AND HYDROPHILIC MOLECULES [PDF]
Ansari, Irfan Aamer, Cavalli, Roberta
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Neurochemical Research, 2023
Pericytes play critical roles in the maintenance of brain vascular homeostasis. However, very little is currently known about how pericytes regulate ischemic stroke-induced brain injury. Inflammation is a key event in the pathobiology of stroke, in which the nod-like receptor protein-3 (NLRP3) inflammasome is involved in, triggering sterile ...
Di, An +12 more
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Pericytes play critical roles in the maintenance of brain vascular homeostasis. However, very little is currently known about how pericytes regulate ischemic stroke-induced brain injury. Inflammation is a key event in the pathobiology of stroke, in which the nod-like receptor protein-3 (NLRP3) inflammasome is involved in, triggering sterile ...
Di, An +12 more
exaly +3 more sources
Phytomedicine, 2010
In this study, we continued to investigate the hypoglycemic activity of Swertia punicea Helmsl., the hypoglycemic and hypolipidemic effects of methylswertianin and bellidifolin from the active ethyl acetate (EtOAc) fraction, and the potential mechanism(s) underlying the improvement of insulin resistance.
L-Y, Tian +5 more
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In this study, we continued to investigate the hypoglycemic activity of Swertia punicea Helmsl., the hypoglycemic and hypolipidemic effects of methylswertianin and bellidifolin from the active ethyl acetate (EtOAc) fraction, and the potential mechanism(s) underlying the improvement of insulin resistance.
L-Y, Tian +5 more
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Planta Medica, 1995
Bellidifolin, isolated from Swertia japonica, was found to be a potent hypoglycemic agent in STZ-induced diabetic rats by both oral and intraperitoneal administration. Bellidifolin significantly lowered the loaded glucose level in normal as well as diabetic rats. Bellidifolin also lowered blood triglyceride levels significantly.
P, Basnet +5 more
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Bellidifolin, isolated from Swertia japonica, was found to be a potent hypoglycemic agent in STZ-induced diabetic rats by both oral and intraperitoneal administration. Bellidifolin significantly lowered the loaded glucose level in normal as well as diabetic rats. Bellidifolin also lowered blood triglyceride levels significantly.
P, Basnet +5 more
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Journal of Toxicology and Environmental Health - Part A: Current Issues, 2017
Bellidifolin, a xanthone compound derived from plants of Gentiana species, is known to exert a variety of pharmacological activities including anti-oxidation, anti-inflammatory and antitumor actions as well as a protective effect on cerebral ischemic nerve injury.
Zhao, Zhi-ying +5 more
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Bellidifolin, a xanthone compound derived from plants of Gentiana species, is known to exert a variety of pharmacological activities including anti-oxidation, anti-inflammatory and antitumor actions as well as a protective effect on cerebral ischemic nerve injury.
Zhao, Zhi-ying +5 more
exaly +3 more sources
Current Pharmaceutical Analysis, 2023
Background: Bellidifolin (BEL) has a decent enemy of myocardial fibrosis impact, and its preparation into nano-micelles can build security and great biocompatibility in vitro and in vivo. The pharmacokinetic assessment of BEL can be utilized as the reason for the security and viability of BEL in clinical use.
Jiaye Tian +7 more
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Background: Bellidifolin (BEL) has a decent enemy of myocardial fibrosis impact, and its preparation into nano-micelles can build security and great biocompatibility in vitro and in vivo. The pharmacokinetic assessment of BEL can be utilized as the reason for the security and viability of BEL in clinical use.
Jiaye Tian +7 more
openaire +1 more source
Planta Medica, 1994
Hypoglycemic activity-guided fractionation led to the isolation of five known xanthones and two triterpenoids from the ethyl acetate soluble fraction of Swertia japonica and their identification was based on spectroscopic methods. One of the triterpenes, thysanolactone, was first isolated from this plant.
P, Basnet +3 more
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Hypoglycemic activity-guided fractionation led to the isolation of five known xanthones and two triterpenoids from the ethyl acetate soluble fraction of Swertia japonica and their identification was based on spectroscopic methods. One of the triterpenes, thysanolactone, was first isolated from this plant.
P, Basnet +3 more
openaire +2 more sources
Preparation, characterization and in vitro study of bellidifolin nano-micelles
RSC Advances, 2022Fan Gao
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