Results 21 to 30 of about 222 (120)
Background Being one of the rapidly growing dementia type diseases in the world, Alzheimer’s disease (AD) has gained much attention from researchers in the recent decades.
Bishajit Sarkar +5 more
doaj +1 more source
Anti-Helicobacter pylori activity of swertianolin, isolated from swertia herb [PDF]
Helicobacter pylori is a Gram-negative, spiral-shaped, motile bacterium present in human stomachs that causes gastric ulcers. A preliminary screening revealed that a methanolic extract of swertia herb demonstrated anti-H. pylori activity.
湯本, 陸 +3 more
core +1 more source
Chemical Composition, Antioxidant and Anticholinesterase Activities of from Russian Federation
Phytochemical study of Gentianella azurea (Bunge) Holub (Gentianaceae) collected in Buryatia Republic (Russian Federation) resulted in the isolation of twenty-one compounds including bellidifolin, bellidin, isobellidifolin, norswertianolin ...
Daniil N. Olennikov +2 more
doaj +1 more source
The present study was to investigate the anti‐diabetic activities of Swertia bimaculata. Based on the glucose consumption of S. bimaculata extractsand different fractions (petroleum, dichloromethane, ethyl acetate, n‐butanol and water extracts) in 3T3‐L1 adipocyte assay, ethanol (ETH) and dichloromethane (DTH) extracts had the most effective potency ...
Zhaoxia Liu +9 more
wiley +1 more source
Inhibition of Aldose Reductase by Gentiana lutea Extracts
Accumulation of intracellular sorbitol due to increased aldose reductase (ALR2) activity has been implicated in the development of various secondary complications of diabetes. Thus, ALR2 inhibition could be an effective strategy in the prevention or delay of certain diabetic complications.
Chandrasekhar Akileshwari +6 more
wiley +1 more source
Bioactivities of centaurium erythraea (Gentianaceae) decoctions: antioxidant activity, enzyme inhibition and docking studies [PDF]
Centaurium erythraea is recommended for the treatment of gastrointestinal disorders and to reduce hypercholesterolemia in ethno-medicinal practice. To perform a top-down study that could give some insight into the molecular basis of these bioactivities ...
Guedes, Laura +5 more
core +1 more source
The Potential of Higher Plants as a Source of New Drugs [PDF]
The plant kingdom is still an untapped reservoir of new molecules with therapeutic potential. A selection of bioactive plant constituents recently discovered are presented with focus on new drugs or lead compounds in an advanced state of development ...
Hostettmann, Kurt +2 more
core +2 more sources
Abstract Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome characterized by pulmonary and systemic congestion resulting from left ventricular diastolic dysfunction and increased filling pressure. Currently, however, there is no evidence on effective pharmacotherapy for HFpEF.
Linna Zhao +9 more
wiley +1 more source
Hypoglycemic effect of Aemotoxylon campechanum on streptozotocin (STZ)-induced diabetic rats [PDF]
Aemotoxylon campechanumの血糖降下作用をSTZ誘発糖尿病ラットを用いて検討したところ,水エキスが空腹時血糖を有意かつ用量依存的に低下させた。そこで,水エキスをメタノール可溶性フラクション及び水溶性フラクションに分画したところ,メタノール可溶性フラクションがより強い作用を示し,100mg/kgの腹腔内投与で空腹時血糖値を37%低下させた。また,水エキス200mg/kg及びメタノール可溶部100mg/kgは空腹時血糖値を35.1 ...
BANSKOTA ArjunH. +3 more
core +1 more source
Phylogenetic examination of crude drugs derived from Yunnanese Swertia plants [PDF]
Aiming to examine whether the genetic background of the crude drugs derived from four Yunnanese Swertia plants and their chemical constituent profiles correlate, we analyzed the nucleotide sequences of their nuclear ribosomal DNA regions including ITS1 ...
Hattori Masao +5 more
core +2 more sources

