Results 21 to 30 of about 222 (120)

Identification of the most potent acetylcholinesterase inhibitors from plants for possible treatment of Alzheimer’s disease: a computational approach

open access: yesEgyptian Journal of Medical Human Genetics, 2021
Background Being one of the rapidly growing dementia type diseases in the world, Alzheimer’s disease (AD) has gained much attention from researchers in the recent decades.
Bishajit Sarkar   +5 more
doaj   +1 more source

Anti-Helicobacter pylori activity of swertianolin, isolated from swertia herb [PDF]

open access: yes, 2023
Helicobacter pylori is a Gram-negative, spiral-shaped, motile bacterium present in human stomachs that causes gastric ulcers. A preliminary screening revealed that a methanolic extract of swertia herb demonstrated anti-H. pylori activity.
湯本, 陸   +3 more
core   +1 more source

Chemical Composition, Antioxidant and Anticholinesterase Activities of from Russian Federation

open access: yesNatural Product Communications, 2017
Phytochemical study of Gentianella azurea (Bunge) Holub (Gentianaceae) collected in Buryatia Republic (Russian Federation) resulted in the isolation of twenty-one compounds including bellidifolin, bellidin, isobellidifolin, norswertianolin ...
Daniil N. Olennikov   +2 more
doaj   +1 more source

Hypoglycemic Activity and Antioxidative Stress of Extracts and Corymbiferin from Swertia bimaculata In Vitro and In Vivo

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2013, Issue 1, 2013., 2013
The present study was to investigate the anti‐diabetic activities of Swertia bimaculata. Based on the glucose consumption of S. bimaculata extractsand different fractions (petroleum, dichloromethane, ethyl acetate, n‐butanol and water extracts) in 3T3‐L1 adipocyte assay, ethanol (ETH) and dichloromethane (DTH) extracts had the most effective potency ...
Zhaoxia Liu   +9 more
wiley   +1 more source

Inhibition of Aldose Reductase by Gentiana lutea Extracts

open access: yesJournal of Diabetes Research, Volume 2012, Issue 1, 2012., 2012
Accumulation of intracellular sorbitol due to increased aldose reductase (ALR2) activity has been implicated in the development of various secondary complications of diabetes. Thus, ALR2 inhibition could be an effective strategy in the prevention or delay of certain diabetic complications.
Chandrasekhar Akileshwari   +6 more
wiley   +1 more source

Bioactivities of centaurium erythraea (Gentianaceae) decoctions: antioxidant activity, enzyme inhibition and docking studies [PDF]

open access: yes, 2019
Centaurium erythraea is recommended for the treatment of gastrointestinal disorders and to reduce hypercholesterolemia in ethno-medicinal practice. To perform a top-down study that could give some insight into the molecular basis of these bioactivities ...
Guedes, Laura   +5 more
core   +1 more source

The Potential of Higher Plants as a Source of New Drugs [PDF]

open access: yes, 1998
The plant kingdom is still an untapped reservoir of new molecules with therapeutic potential. A selection of bioactive plant constituents recently discovered are presented with focus on new drugs or lead compounds in an advanced state of development ...
Hostettmann, Kurt   +2 more
core   +2 more sources

The total xanthones extracted from Gentianella acuta alleviates HFpEF by activating the IRE1α/Xbp1s pathway

open access: yesJournal of Cellular and Molecular Medicine, Volume 28, Issue 11, June 2024.
Abstract Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome characterized by pulmonary and systemic congestion resulting from left ventricular diastolic dysfunction and increased filling pressure. Currently, however, there is no evidence on effective pharmacotherapy for HFpEF.
Linna Zhao   +9 more
wiley   +1 more source

Hypoglycemic effect of Aemotoxylon campechanum on streptozotocin (STZ)-induced diabetic rats [PDF]

open access: yes, 2003
Aemotoxylon campechanumの血糖降下作用をSTZ誘発糖尿病ラットを用いて検討したところ,水エキスが空腹時血糖を有意かつ用量依存的に低下させた。そこで,水エキスをメタノール可溶性フラクション及び水溶性フラクションに分画したところ,メタノール可溶性フラクションがより強い作用を示し,100mg/kgの腹腔内投与で空腹時血糖値を37%低下させた。また,水エキス200mg/kg及びメタノール可溶部100mg/kgは空腹時血糖値を35.1 ...
BANSKOTA ArjunH.   +3 more
core   +1 more source

Phylogenetic examination of crude drugs derived from Yunnanese Swertia plants [PDF]

open access: yes, 2014
Aiming to examine whether the genetic background of the crude drugs derived from four Yunnanese Swertia plants and their chemical constituent profiles correlate, we analyzed the nucleotide sequences of their nuclear ribosomal DNA regions including ITS1 ...
Hattori Masao   +5 more
core   +2 more sources

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