Comparison of 24-hour versus random urine samples for determination and quantification of Bence Jones protein in a South African population [PDF]
Background: The International Myeloma Working Group and College of American Pathologists recommend a 24-h urine collection to determine the Bence Jones protein (BJP) excretion level for monitoring treatment response in patients with multiple myeloma (MM).
Ashandree Reddy+2 more
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Novel Approach to Rule-Out Unnecessary Urine Bence Jones Protein Testing: A Serum Free Light Chain Algorithm [PDF]
Background/Objectives: Bence Jones proteins (BJPs) are monoclonal immunoglobulin free light chains (FLCs) that appear in the urine of patients with plasma cell disorders, including multiple myeloma (MM), Waldenström’s macroglobulinemia (WM), or light ...
Vanessa García Moreira+10 more
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What's in a name? Bence Jones protein. [PDF]
Plasma cell disorders are important in the differential diagnosis of acute kidney injury and of renal impairment with proteinuria. One or more of several mechanisms can be involved, such as cast nephropathy, deposition of monoclonal immunoglobulins, formation of amyloid fibrils, hypercalcaemia, hyperuricaemia and a variety of tubular syndromes. Various
Rathore R, Coward RA, Woywodt A.
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THE FATE OF INJECTED BENCE JONES PROTEIN [PDF]
Bence Jones protein injected into rabbits was excreted rapidly into the urine. The excreted protein retained the physicochemical and immunochemical properties of the injected Bence Jones protein. In spite of the rapid excretion, a significant portion of the injected Bence Jones protein was found to be metabolized. After reinjection of radioactive Bence
Franz Meyer, Frank W. Putnam
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On the localisation of antigenic determinants in a Bence Jones protein [PDF]
Abstract 1. 1. The presence of a low molecular weight protein (1.2 S), having antigenic determinants in common with the homologous Bence Jones protein (3.4 S), has been observed in the urine of a patient with multiple myeloma. Its amino acid composition and α -NH 2 -terminal amino acid residue make it likely that the 1.2 S component is a protein
H.G. van Eyk, K Myszkowska
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Bence-Jones protein as the form of nano-scaled β-stacked supramolecular aggregates
. The formation in β-structured protein aggregates in tissues and fluids of the body is one of the most dangerouse complications of various diseases.
N. M. Voroshylova+2 more
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Nephrotoxic Potential of Bence Jones Proteins [PDF]
The renal manifestations of diseases associated with the production of monoclonal light chains--myeloma (cast) nephropathy, light-chain deposition disease, and amyloidosis AL--result from the deposition of certain Bence Jones proteins as tubular casts, basement-membrane precipitates, or fibrils, respectively.
Alan Solomon+2 more
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Four crystal forms of a Bence-Jones protein. [PDF]
Four crystal forms have been grown and characterized by X-ray diffraction of a Bence-Jones protein collected from the urine of a multiple myeloma patient more than 40 years ago. Closely related tetragonal and orthorhombic forms belonging to space groups P4(3)2(1)2 and P2(1)2(1)2(1), with unit-cell parameters a = b = 68.7, c = 182.1 and a = 67.7, b = 69.
Makino DL+2 more
europepmc +7 more sources
Fibrillary Glomerulonephritis and Multiple Myeloma: A Case Report and Literature Review [PDF]
Introduction: Fibrillary glomerulonephritis (FGN) is a rare form of immune complex-mediated primary glomerular disease frequently coexisting with malignancies or autoimmune diseases.
Taiki Ishida+9 more
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A study of Bence‐Jones protein, and of the metabolism in three cases of Bence‐Jones proteinuria
Frederick Gowland Hopkins, H Savory
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