Results 171 to 180 of about 5,397 (195)
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Contribution A L’Etude Des Proteines De Bence-Jones
Acta Clinica Belgica, 1956SummaryA biochemical study of fourteen cases of multiple myeloma with Bence-Jones proteins present in the urine, is made. Bence-Jones proteins have several properties in common which distinguish them from the other normal or abnormal serum proteins. Thanks to their low molecular weight, they pass through the kidney and can be easily characterised in ...
H. Vis, R. Crokaert
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Detection of Bence-Jones protein in practice
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2000The monoclonal gammopathies are characterized by the presence in serum and/or urine of a monoclonal, intact immunoglobulin or fragment, a so-called monoclonal component, produced by a B-cell clone that has undergone a genetic transformation. The clinical conditions accompanying monoclonal components encompass a wide spectrum, ranging from an entirely ...
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Thermodynamic and hydrodynamic study of Bence-Jones proteins
Molecular Biology, 2009Four Bence-Jones proteins were investigated by CD, fluorescence and analytical ultracentrifugation methods at physiological conditions (10 mM phosphate buffer, pH 7.0, 100 mM NaCl). A joint analysis of optical melting curves for proteins and their fragments were demonstrated that protein VAD has reduced stability of its constant half, which correlates ...
V. M. Tishchenko +2 more
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Action of Trypsin on Bence-Jones Protein Derivatives
Nature, 1961IT is well known that the proteolytic enzyme trypsin fails to hydrolyse native proteins, or hydrolyses them to only a very small extent. The denaturation of protein substrate is therefore a customary preliminary operation in all work involving the action of trypsin on proteins. We report here the effect of trypsin on some chemical derivatives of a pure
Romano Zito, Umberto Ferrini
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DETERMINATION OF BENCE JONES PROTEIN IN THE URINE
JAMA, 1960Although the introduction of electrophoretic methods has led to a much improved characterization of the abnormal globulins which occur in patients with multiple myeloma, the simple determination of the presence of Bence Jones protein in the urine has remained as important as ever for the diagnosis of multiple myeloma.
Isidore Snapper, Richard O. Ores
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Kinetics of dimerization of the bence-jones protein Au
Biophysical Chemistry, 1978The dimerization reactions of complete Bence-Jones protein Au (VC-Au) and of its variable fragment (V-Au) were compared in 0.2 M (ionic strength) sodium phosphate buffer, pH 6.8 at 20 degrees C. The dimerization constant for VC-Au (6.6 X 10(4) M-1) was slightly smaller than a previously published value for the fragment (1.1 X 10(5) M-1).
Hiroshi Maeda +5 more
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Detection of Bence-Jones Protein in Serum by Immunoblotting
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1996To detect Bence-Jones protein (BJP) in serum we precipitated intact immunoglobulins (Ig) using polyethylene glycol (PEG) and subjected the BJP in solution to electrophoresis in agarose gel, followed by transfer to a polyvinylidene difluoride membrane, and immunoenzymatic staining (successively using rabbit anti-human light/heavy chain of Ig ...
E T Backer, A Brand
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Small-angle scattering of Bence-Jones protein
Biochimica et Biophysica Acta (BBA) - Specialized Section on Biophysical Subjects, 1964Abstract Solutions of Bence-Jones protein in water have been studied at concentrations of 1–4%. By measuring the absolute intensity of scattered radiation, a molecular weight of 43000 was found in complete agreement with ultracentrifuge results; in addition, an internal hydration of 0.32 g water per g protein was determined.
P. Mittelbach +3 more
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Bence Jones Protein und Amyloid
Zeitschrift für Die Gesamte Experimentelle Medizin einschließlich experimentelle Chirurgie, 1968Die Frage der Entstehungsweise des Amyloids durch eine Antigen-Antikorper-Reaktion wurde erneut uberpruft:Epstein u.Gross (1964) hatten einen naturlicherweise auftretenden Antikorper beschrieben, der mit Bence Jones Protein (BJP) reagierte, undOsserman u. Mitarb. (1964) stellten fest, das ein Hauptbestandteil des Amyloids BJP sei.
D. Sellin, O. Haferkamp
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Urea Denaturation of Bence Jones Proteins* [PDF]
The Journal of Biochemistry, 1973 Kozo Hamaguchi +2 more
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