Results 41 to 50 of about 11,801 (249)

Nonsecretory Multiple Myeloma Presenting as an Intestinal Tumor

open access: yesCase Reports in Hematology, 2015
We report a case of a 43-year-old Caucasian man who presented with colicky abdominal pain and microcytic hypochromic anemia. The patient underwent a colonoscopy where a tumor was seen in the ascending colon; histology showed plasmacytoma of the colon ...
Diana Triantafyllopoulou   +7 more
doaj   +1 more source

Renal failure in patients with multiple myeloma

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2015
Renal dysfunction is encountered in 20-25% of patients with multiple myeloma (MM) at the time of diagnosis. There is often a precipitating event. Several biochemical and clinical correlations with renal failure in MM have been reported.
Samir H Almueilo
doaj   +1 more source

The ubiquitin-proteasome pathway in Huntington's disease. [PDF]

open access: yes, 2008
The accumulation of mutant protein is a common feature of neurodegenerative disease. In Huntington's disease, a polyglutamine expansion in the huntingtin protein triggers neuronal toxicity.
Finkbeiner, Steven, Mitra, Siddhartha
core   +2 more sources

Free light chains of immunoglobulins in the diagnosis and prognosis of multiple myeloma

open access: yesAlʹmanah Kliničeskoj Mediciny, 2017
Background: Analysis of free light chains of immunoglobulins (FLC) in the serum is an effective method in the diagnosis of multiple myeloma. Plasma cells produce two types of FLC: κand λ-FLC.
N. V. Lyubimova   +3 more
doaj   +1 more source

Systemic Mastocytosis Associated with “Smoldering” Multiple Myeloma

open access: yesDiagnostics, 2021
A 79-year-old woman presented with a long history of peripheral eosinophilia. Previous right hemicolectomy for colonic polyposis was reported. Laboratory tests were notable for mild macrocitic anaemia and eosinophilia. β2 microglobulin and serum tryptase
Magda Zanelli   +7 more
doaj   +1 more source

Microencapsulation technology by nature: Cell derived extracellular vesicles with therapeutic potential [PDF]

open access: yes, 2013
Cell derived extracellular vesicles are submicron structures surrounded by phospholipid bilayer and released by both prokaryotic and eukaryotic cells.
Buzás, E., Falus, A., Kittel, Ágnes
core   +1 more source

Folding of small disulfide-rich proteins : clarifying the puzzle [PDF]

open access: yes, 2006
Premi a l'excel·lència investigadora. Àmbit de les Ciències Experimentals. 2008The process by which small proteins fold to their native conformations has been intensively studied over the last few decades.
Apuy   +73 more
core   +2 more sources

Difficulties evaluating hematological response in patients with multiple myeloma and dialysis - dependent renal impairment

open access: yesТерапевтический архив, 2019
Aim: to determine serum free light chains (FLC) level by patients with multiple myeloma (MM) and dialysis - dependent renal impairment in which the amount Bence Jones (BJ) protein in the urine met the criteria of hematological response.
I G Rekhtina   +2 more
doaj   +1 more source

Amino Acids of Bence-Jones Protein

open access: yesExperimental Biology and Medicine, 1950
Summary1. Hydrolysates of a sample of Bence-Jones protein isolated from the urine of a patient with multiple myelomatosis were examined by paper chromatography. Quantitative estimations of 18 amino acids were also made by microbiological methods.2. The protein was characterized by a very low content of methionine (0.12%) and by relatively large amounts
Roberts, E, Ramasarma, GB, Lewis, HB
openaire   +2 more sources

Navigating the evolving management of smoldering multiple myeloma

open access: yesHemaSphere, Volume 10, Issue 1, January 2026.
Abstract Smoldering multiple myeloma (SMM) represents an intermediate clinical stage between monoclonal gammopathy of undetermined significance (MGUS) and symptomatic multiple myeloma (MM). SMM carries a highly variable risk of progression to MM, requiring individualized risk stratification to guide management.
M. Bakri Hammami   +6 more
wiley   +1 more source

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