Results 41 to 50 of about 11,801 (249)
Nonsecretory Multiple Myeloma Presenting as an Intestinal Tumor
We report a case of a 43-year-old Caucasian man who presented with colicky abdominal pain and microcytic hypochromic anemia. The patient underwent a colonoscopy where a tumor was seen in the ascending colon; histology showed plasmacytoma of the colon ...
Diana Triantafyllopoulou +7 more
doaj +1 more source
Renal failure in patients with multiple myeloma
Renal dysfunction is encountered in 20-25% of patients with multiple myeloma (MM) at the time of diagnosis. There is often a precipitating event. Several biochemical and clinical correlations with renal failure in MM have been reported.
Samir H Almueilo
doaj +1 more source
The ubiquitin-proteasome pathway in Huntington's disease. [PDF]
The accumulation of mutant protein is a common feature of neurodegenerative disease. In Huntington's disease, a polyglutamine expansion in the huntingtin protein triggers neuronal toxicity.
Finkbeiner, Steven, Mitra, Siddhartha
core +2 more sources
Free light chains of immunoglobulins in the diagnosis and prognosis of multiple myeloma
Background: Analysis of free light chains of immunoglobulins (FLC) in the serum is an effective method in the diagnosis of multiple myeloma. Plasma cells produce two types of FLC: κand λ-FLC.
N. V. Lyubimova +3 more
doaj +1 more source
Systemic Mastocytosis Associated with “Smoldering” Multiple Myeloma
A 79-year-old woman presented with a long history of peripheral eosinophilia. Previous right hemicolectomy for colonic polyposis was reported. Laboratory tests were notable for mild macrocitic anaemia and eosinophilia. β2 microglobulin and serum tryptase
Magda Zanelli +7 more
doaj +1 more source
Microencapsulation technology by nature: Cell derived extracellular vesicles with therapeutic potential [PDF]
Cell derived extracellular vesicles are submicron structures surrounded by phospholipid bilayer and released by both prokaryotic and eukaryotic cells.
Buzás, E., Falus, A., Kittel, Ágnes
core +1 more source
Folding of small disulfide-rich proteins : clarifying the puzzle [PDF]
Premi a l'excel·lència investigadora. Àmbit de les Ciències Experimentals. 2008The process by which small proteins fold to their native conformations has been intensively studied over the last few decades.
Apuy +73 more
core +2 more sources
Aim: to determine serum free light chains (FLC) level by patients with multiple myeloma (MM) and dialysis - dependent renal impairment in which the amount Bence Jones (BJ) protein in the urine met the criteria of hematological response.
I G Rekhtina +2 more
doaj +1 more source
Amino Acids of Bence-Jones Protein
Summary1. Hydrolysates of a sample of Bence-Jones protein isolated from the urine of a patient with multiple myelomatosis were examined by paper chromatography. Quantitative estimations of 18 amino acids were also made by microbiological methods.2. The protein was characterized by a very low content of methionine (0.12%) and by relatively large amounts
Roberts, E, Ramasarma, GB, Lewis, HB
openaire +2 more sources
Navigating the evolving management of smoldering multiple myeloma
Abstract Smoldering multiple myeloma (SMM) represents an intermediate clinical stage between monoclonal gammopathy of undetermined significance (MGUS) and symptomatic multiple myeloma (MM). SMM carries a highly variable risk of progression to MM, requiring individualized risk stratification to guide management.
M. Bakri Hammami +6 more
wiley +1 more source

