Results 51 to 60 of about 5,397 (195)

Púrpura: manifestação de amiloidose sistémica primária.

Acta Médica Portuguesa, 2009
Primary Systemic Amyloidosis (AL) is the most frequent form of systemic amyloidosis and its morbilility is associated with immunoglobulin light chains deposition in vital organs. The mucocutaneous manifestations occur in about 30-40% of the cases and are
Sara Lestre, Andreia Gonçalves, Alexandre João, Ana Ferreira, Margarida Apetato   +4 more
doaj   +1 more source

Amino-acid Composition of Bence–Jones Protein [PDF]

Nature, 1949
OUR knowledge of the amino-acid composition of Bence–Jones protein is still incomplete. Recently, Dent1 has analysed a specimen of Bence–Jones protein, using paper partition chromatography, with regard to its amino-acid composition. He found that the specimen contained all the common amino-acids except methionine and hydroxyproline.
John F. Wilkinson, J. E. Kench, S. C. Papastamatis   +2 more
openaire   +2 more sources

Intestinal Perforation Secondary to Bortezomib‐Induced Autonomic Neuropathy

Clinical Case Reports, Volume 13, Issue 4, April 2025.
ABSTRACT It is essential to evaluate both the patient's prior conditions and the severity of the current clinical presentation when deciding on BTZ toxicity management. It seems prudent to consider the permanent discontinuation of the drug in patients who have experienced at least grade 3 intestinal neuropathy and have structural abnormalities or other
Jose Antonio Sánchez Salas, Maria Jose Moreno Belmonte, Andrea Poveda García, Estela Ruiz Ruiz, Eva Soler Espejo, Valentin Cabanas Perianes, Ana María García Hernandez   +6 more
wiley   +1 more source

Prediction of mobilized hematopoietic stem cell yield in patients with multiple myeloma: Usefulness of whole-body MRI-derived indices.

PLoS ONE, 2023
IntroductionHigh-dose chemotherapy followed by autologous stem cell transplant is the mainstay of treatment for multiple myeloma (MM). The purpose of this study was to evaluate the ability of MRI-derived indices to predict mobilized hematopoietic stem ...
Miyuki Takasu, Ryo Higashino, Takahiro Sueoka, Saki Kawai, Nobuko Tanitame, Akihisa Tamura, Makoto Iida, Takakazu Kawase, Tatsuo Ichinohe, Kazuo Awai   +9 more
doaj   +1 more source

Chronic Viral Infections and Al Amyloidosis: An Uncommon Association

Clinical Case Reports, Volume 13, Issue 4, April 2025.
ABSTRACT AL‐amyloidosis is caused by deposition of pathological insoluble proteins in organs and tissues. HIV infection is a multi‐system disorder causing chronic inflammation. We report a case of AL‐amyloidosis associated with HIV suggesting that HIV‐associated immune dysregulation might be critical for pathogenesis of plasma cells dyscrasias and then
Alberto Palladini, Gabriele Cusumano, Ottavio Martellucci, Antonietta Gigante, Gabriella D'Ettorre, Maria Teresa Petrucci, Maurizio Muscaritoli, Mariangela Palladino   +7 more
wiley   +1 more source

Mass Spectrometry–Based Proteomics in Clinical Diagnosis of Amyloidosis and Multiple Myeloma: A Review (2012–2024)

Journal of Mass Spectrometry, Volume 60, Issue 3, March 2025.
ABSTRACT Proteomics is nowadays increasingly becoming part of the routine clinical practice of diagnostic laboratories, especially due to the advent of advanced mass spectrometry techniques. This review focuses on the application of proteomic analysis in the identification of pathological conditions in a hospital setting, with a particular focus on the
Katerina Kratka, Pavel Sistik, Ivana Olivkova, Pavlina Kusnierova, Zdenek Svagera, David Stejskal   +5 more
wiley   +1 more source

Acute Myeloid Leukaemia with Plasmacytosis

Journal of Islamic International Medical College, 2016
Association of acute myeloid leukaemia with bone marrow plasmacytosis is a rare phenomenon with diverse underlying pathogenetic mechanisms. We report a case of a 75 years old diabetic male diagnosed as suffering with plasmacytosis.
Yasmin Akhtar, Saqib Qayyum Ahmad, Shahid Jamal
doaj  

Type-I Cryoglobulinaemia Associated to Monoclonal Gammapathy of Undetermined Significance

Prague Medical Report, 2020
Cryoglobulins are immunoglobulins that undergo reversible precipitation at cold temperatures. Monoclonal type-I cryoglobulinaemia is the least frequent and is associated to hematological diseases such as multiple myeloma, Waldenström’s macroglobulinaemia,
Juan Manuel Duarte, Paloma Ocampo, Silvia Graciela Ramos, Orlando Gabriel Carballo, Ricardo E. Barcia, Cecilia Elena Arévalo   +5 more
doaj   +1 more source

Nasal septum extramedullary plasmacytoma [PDF]

Vojnosanitetski Pregled, 2013
Introduction. Plasmacytomas are malignant tumors characterized by abnormal monoclonal proliferation of plasma cells. They originate in either bone - solitary osseous plasmacytoma, or in soft tissue - extramedullary plasmacytoma (EMP).
Belić Branislav, Mitrović Slobodanka, Arsenijević Snežana, Erdevički Ljiljana, Stojanović Jasmina, Stojanović Stevan, Stolić Radojica   +6 more
doaj   +1 more source

Prozone effect of serum IgE levels in a case of plasma cell leukemia

Journal of Hematology & Oncology, 2010
We describe a case of multiple myeloma (MM) and secondary plasma cell leukemia (PCL) secreting IgE-kappa immunoglobulin. To our knowledge, only 2 cases of IgE-producing secondary PCL have been reported in the medical literature.
Talamo Giampaolo, Castellani William, Dolloff Nathan G   +2 more
doaj   +1 more source