Results 71 to 80 of about 11,801 (249)
PLoS ONE, 2023 IntroductionHigh-dose chemotherapy followed by autologous stem cell transplant is the mainstay of treatment for multiple myeloma (MM). The purpose of this study was to evaluate the ability of MRI-derived indices to predict mobilized hematopoietic stem ...
Miyuki Takasu +9 more
doaj +1 more source
Amino-acid Composition of Bence–Jones Protein [PDF]
Nature, 1949 OUR knowledge of the amino-acid composition of Bence–Jones protein is still incomplete. Recently, Dent1 has analysed a specimen of Bence–Jones protein, using paper partition chromatography, with regard to its amino-acid composition. He found that the specimen contained all the common amino-acids except methionine and hydroxyproline.
S C, PAPASTAMATIS +2 more
openaire +2 more sources
Targeting ATM pathway for therapeutic intervention in cancer [PDF]
, 2012 The Ataxia Telangiectasia Mutated gene encodes the ATM protein, a key element in the DNA damage response (DDR) signalling pathway responsible for maintaining genomic integrity within the cell.
Chakarov, Stoyan +4 more
core +3 more sources
Immunity, Inflammation and Disease, Volume 13, Issue 8, August 2025.ABSTRACT Background Multiple myeloma (MM) is a common malignant tumor of the hematological system caused by the malignant proliferation of plasma cells, characterized by the production of M proteins and CRAB symptoms. Among them, the Immunoglobulin G MM is the most common, while the IgG4‐MM is extremely rare.
Jun Long +4 more
wiley +1 more source
Multiple myeloma invasion of the central nervous system [PDF]
, 2012 Introduction. Multiple myeloma (MM) is characterized by the presence of neoplastic proliferating plasma cells. The tumor is generally restricted to the bone marrow.
Marjanović Slobodan +7 more
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eJHaem, Volume 6, Issue 4, August 2025.Abstract Immunoglobulin light chain (AL) and wild‐type transthyretin (ATTRwt) amyloidosis, while sharing similar clinical presentations, require distinct treatments. We report a rare case of a 75‐year‐old man with heart failure diagnosed with concurrent AL and ATTRwt cardiac amyloidosis.
Taiki Nishihara +10 more
wiley +1 more source
Acute Myeloid Leukaemia with Plasmacytosis
Journal of Islamic International Medical College, 2016 Association of acute myeloid leukaemia with bone marrow plasmacytosis is a rare phenomenon with diverse underlying pathogenetic mechanisms. We report a case of a 75 years old diabetic male diagnosed as suffering with plasmacytosis.
Yasmin Akhtar, Saqib Qayyum Ahmad, Shahid Jamal
doaj
Prozone effect of serum IgE levels in a case of plasma cell leukemia
Journal of Hematology & Oncology, 2010 We describe a case of multiple myeloma (MM) and secondary plasma cell leukemia (PCL) secreting IgE-kappa immunoglobulin. To our knowledge, only 2 cases of IgE-producing secondary PCL have been reported in the medical literature.
Talamo Giampaolo +2 more
doaj +1 more source
Type-I Cryoglobulinaemia Associated to Monoclonal Gammapathy of Undetermined Significance
Prague Medical Report, 2020 Cryoglobulins are immunoglobulins that undergo reversible precipitation at cold temperatures. Monoclonal type-I cryoglobulinaemia is the least frequent and is associated to hematological diseases such as multiple myeloma, Waldenström’s macroglobulinaemia,
Juan Manuel Duarte +5 more
doaj +1 more source
New Methods in Treatment of Renal failure in Patients with Multiple Myeloma: A Review with Immunological Approach. [PDF]
, 2017 Multiple myeloma (MM), as one of a variety of autoimmune diseases, affects the immune system and, on the other hand, is considered to be a hematologic impairment.
Iranparast, Sara. +2 more
core +1 more source