Results 81 to 90 of about 11,801 (249)

Experimental and Computational Insights into the Structural Dynamics of the Fc Fragment of IgG1 Subtype from Biosimilar VEGF‐Trap

open access: yesSmall Structures, Volume 6, Issue 8, August 2025.
The constant fragment (Fc) of the immunoglobulin G1 (IgG1) subtype is a widely used scaffold for designing advanced therapeutics. Herein, together with the integration of experimental and computational techniques, this study reveals the structural dynamics of the N‐glycan‐bound Fc fragment of IgG1 from VEGF‐Trap, providing a new insight into enhancing ...
Ebru Destan   +11 more
wiley   +1 more source

Total Neoadjuvant Therapy Versus Conventional Neoadjuvant Therapy for Rectal Cancer: Cost Analysis in a Public Healthcare System

open access: yesANZ Journal of Surgery, Volume 95, Issue 7-8, Page 1493-1508, July/August 2025.
Costs of neoadjuvant therapy. ABSTRACT Purpose Total neoadjuvant therapy (TNT) has become the standard of care in locally advanced rectal cancer, but its economic impact is unclear. This study compares the cost of TNT with conventional neoadjuvant therapy (CNT), consisting of either short‐course radiotherapy or long‐course chemoradiotherapy, within a ...
Ishraq Murshed   +6 more
wiley   +1 more source

Multiple myeloma presenting as acute tubulointerstitial nephritis

open access: yesAutopsy and Case Reports, 2021
Background: Acute tubulointerstitial nephritis (ATIN) is a very rare paraneoplastic manifestation in patients with multiple myeloma (MM). It is an uncommon pattern of renal disease in such patients.
Ying Long   +6 more
doaj  

Multiple Myeloma in Indonesia [PDF]

open access: yes, 2011
Tujuan: Melihat karakteristik klinis pasien mieloma multipel di Indonesia.Metode: studi deskriptif, potong lintang, multisenter, dilakukan pada November 2008 sampai dengan November 2009.
Reksodiputro, A. H. (Arry)   +2 more
core  

Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD‐ADRD): Executive summary of recommendations for primary care

open access: yesAlzheimer's &Dementia, Volume 21, Issue 6, June 2025.
Abstract US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence‐based guideline was developed to empower all—including primary care—clinicians to implement a structured approach for evaluating a ...
Alireza Atri   +10 more
wiley   +1 more source

Modern Immunology: Cells and Molecules [PDF]

open access: yes, 1974
In this presentation I shall discuss 1) some historical highlights n the field of immunology; 2) the molecules of immunity, particularly the immunoglobulins; and 3) the cells of immunity, particularly the immunocytes.
Mullinax, Franklin
core   +1 more source

Spectrum of Myeloma with Varied Presentations at a Tertiary Care Centre

open access: yesJournal of Medical Sciences and Health
Introduction: Multiple myeloma is a disorder caused by neoplastic proliferation of malignant plasma cells. It comprises about 15% of all hematologic malignancies and contributes to 1% of cancer deaths.
Sabiha Tasneem Shaik   +2 more
doaj   +1 more source

The Quest for Antibodies and Other Acquired Immune Receptors: A Historical Perspective

open access: yesInternational Journal of Immunogenetics, Volume 52, Issue 3, Page 125-134, June 2025.
ABSTRACT The diversity of antibody molecules has for decades been an unsolved enigma that has attracted wide interest among biologists. Parallel to the accumulation of experimental evidence, progress in antibody research was also driven by the theoretical debate that played a particularly prominent role, at least until the entry of molecular biology ...
Andrea De Lerma Barbaro   +5 more
wiley   +1 more source

Extramedullary plasmacytoma of the tonsil: A new management [PDF]

open access: yes, 2015
Introduction: Extramedullary plasmacytoma (EMP) is a rare tumor of all plasma cell neoplasms. The tumor is mainly localized in the head and neck region, but rarely involving the tonsil.
Costanzo, R.   +11 more
core  

Home - About - Disclaimer - Privacy