Results 71 to 80 of about 1,575,498 (276)

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

RockCloud-Align: A High-Precision Benchmark for Rock-Mass Point-Cloud Registration

Remote Sensing
Rock-mass point-cloud registration is a critical yet challenging task in the fields of geology and engineering. Currently, the lack of dedicated datasets for rock-mass point-cloud registration significantly limits the development and application of ...
Yunbiao Wang, Dongbo Yu, Lupeng Liu, Jun Xiao   +3 more
doaj   +1 more source

RSI-CB: A Large-Scale Remote Sensing Image Classification Benchmark Using Crowdsourced Data

Sensors, 2020
Image classification is a fundamental task in remote sensing image processing. In recent years, deep convolutional neural networks (DCNNs) have experienced significant breakthroughs in natural image recognition.
Haifeng Li, Xin Dou, Chao Tao, Zhixiang Wu, Jie Chen, Jian Peng, Min Deng, Ling Zhao   +7 more
doaj   +1 more source

Minimally Clinically Important Difference of the Clinical Assessment Scale in Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The Clinical Assessment Scale in Autoimmune Encephalitis (CASE) tracks disease severity in autoimmune encephalitis (AE), but no threshold for significant change exists. We aimed to determine the minimally clinically important difference (MCID) for CASE.
Yihui Goh, Yoon Hee Shin, Soo Hyun Ahn, Su Yee Mon, Soo Jean Shin, Woo‐Jin Lee, Yoonhyuk Jang, Myoung‐Jin Jang, Soon‐Tae Lee   +8 more
wiley   +1 more source

Analiza stanja pri uvajanju sodobnega višinskega sistema : Status of the new height system development [PDF]

Geodetski Vestnik, 2011
V prispevku je predstavljen predlog za novo oštevilčevanje nivelmanskih poligonov in reperjev. Obravnavana je tudi analiza natančnosti izmerjenih višinskih razlik, opravljena na podlagi odstopanj obojestransko merjenih višinskih razlik in odstopanj pri ...
Božo Koler, Nuša Vardjan, Tilen Urbančič   +2 more
doaj  

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

FishMark: A Linked Data Application Benchmark [PDF]

, 2012
. FishBase is an important species data collection produced by the FishBase Information and Research Group Inc (FIN), a not-forprofit NGO with the aim of collecting comprehensive information (from the taxonomic to the ecological) about all the world’s ...
Alkiviadous, S., Bail, S., Concalves, R. S., Garilao, Cristina, Parsia, B., van Harmelen, M., Workman, D.   +6 more
core   +1 more source

Benchmark Parameters for CMB Polarization Experiments

, 2002
The recently detected polarization of the cosmic microwave background (CMB) holds the potential for revealing the physics of inflation and gravitationally mapping the large-scale structure of the universe, if so called B-mode signals below 10^{-7}, or ...
A. Challinor, A. de Oliveira-Costa, A. Lewis, A.H. Jaffe, C. Heiles, C. Heiles, E. Newman, E.F. Bunn, E.L. Wright, E.M. Leitch, F. Couchot, J. Kovac, J.N. Goldberg, J.P. Hamaker, K. Benabed, L. Knox, M. Hedman, M. Kamionkowski, M. Tegmark, M. Tegmark, M. White, M. Zaldarriaga, M. Zaldarriaga, Matias Zaldarriaga, Matthew M. Hedman, P. Fosalba, S. Prunet, U. Seljak, V.H. Rumsey, W. Hu, W. Hu, Wayne Hu, X. Wang, X. Zhang   +33 more
core   +1 more source

Evaluation of a Novel Electric Health Record Sidecar Application to Display Rheumatoid Arthritis Clinical Outcomes During Clinic Visits: Results of a Stepped‐Wedge Cluster Randomized Pragmatic Trial

Arthritis Care &Research, EarlyView.
Objective We developed a novel electronic health record sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk, Jing Li, Cathy Nasrallah, Cherish Wilson, Alicia Hamblin, Christine Hariz, Cammie Young, Stephen Shiboski, Emma Kersey, Mary Nakamura, Judith F. Ashouri, Mehrdad Matloubian, Andrew J. Gross, Jennifer Barton, Beth Berrean, Jonathan Prugh, Jinoos Yazdany   +16 more
wiley   +1 more source