Results 101 to 110 of about 147,603 (316)
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
City of Bend SE Area interceptor : preliminary evaluation
55 pp. Bookmarks supplied by UO. Maps, charts, tables, appendix. Published December, 2005. Captured August 14, 2009.The goal of this project is to provide a long-term option for providing sewer service to the SE Bend Area.
Bend (Or.), MWH Americas, Inc.
core
Peran Media Massa dalam Mencegah Konflik
Indonesia is a country with diversified ethnics, religions and races. Without spirit of tolerance this condition can emerge conflict and disunion. Mass media is one of instruments in mass communication process that filter and select news and conflict to ...
Bend Abidin Santosa
doaj
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
29 pp. Bookmarks supplied by UO. Tables, charts, figures. Published April, 2008. Captured March 24, 2009.The Bend Water Reclamation Facility (WRF) currently consists of the following liquid treatment processes: preliminary treatment; primary ...
Carollo Engineers, Bend (Or.)
core
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Astrocyte heterogeneity in brain metastases
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
Bend Notice of Adopted Amendment (2008-02-21)
12 pp. Adopted 2008-02-21. Department of Land Conservation and Development Notice of Adopted AmendmentThe initial Plan Amendment (adopted on October 3.
Bend (Or.)
core
Food insecurity is a pervasive public health issue in the United States. While food pantries attempt to alleviate this issue, their effectiveness is limited by structural and logistical barriers that affect service accessibility.
Jackson F. Stone +6 more
doaj +1 more source

