Results 111 to 120 of about 177,484 (300)

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

open access: yesMolecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis   +20 more
wiley   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Bend urban area transportation system plan

open access: yes, 2006
231 pp. Bookmarks modified by UO. Referenced maps included. Last amended June 21, 2006; captured July 27, 2006.The TSP provides city of Bend compliance with the requirements set out in Oregon Administrative Rule: 660-12.
Bend (Or.)
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Bend Notice of Adopted Amendment (2007-09-17)

open access: yes, 2007
8 pp. Adopted 2007-09-17. Department of Land Conservation and Development Notice of Adopted AmendmentAmend Ordinance No. NS-2016. by changing the zoning of 19.91 acres of land on the City of Bend Zoning Map from Residential Urban Standard Density (RS) to
Bend (Or.)
core  

Bend Metro Park and Recreation District 2006-2010 strategic plan [PDF]

open access: yes, 2006
19 pp. Bookmarks supplied by UO. Charts, illus. Adopted February 7, 2006. Captured February 8, 2009.Mission statement: To enhance the vitality of our community by promoting healthy lifestyles and enriching Bend's unique character with exceptional ...
Bend Metro Park and Recreation District   +1 more
core  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Bend Notice of Adopted Amendment (2006-05-01)

open access: yes, 2006
52 pp. Adopted 2006-05-01. Department of Land Conservation and Development Notice of Adopted AmendmentAMEND THE .BEND URBAN AREA ZONING. MAP FROM SR 2 1 / 2 Density Residential) ( S u b u r b a n Low Density) Zone t o RS ( R e s i d e n t i a l U r b a n
Bend (Or.)
core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

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