Results 41 to 50 of about 8,225,610 (293)

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Study on Shear Wave Attenuation Laws in Granular Sediments Based on Bender Element Test Simulations

Journal of Marine Science and Engineering
The propagation characteristics of shear waves in granular sediments are usually used to assess the dynamic response and liquefaction potential of marine engineering foundations.
Jingyu Tan, Yong Wang, Xuewen Lei, Jingqiang Miao   +3 more
doaj   +1 more source

A unified approach to link small-strain shear modulus and liquefaction resistance of pumiceous sand

Soils and Foundations, 2022
Natural pumiceous (NP) sands containing pumice particles, a type of volcanic soil, are commonly found in the central part of the North Island in New Zealand.
Mohammad Bagher Asadi, Rolando P. Orense, Mohammad Sadeq Asadi, Michael J. Pender   +3 more
doaj   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Effect of earthquake excitation on circular tunnels: Numerical and experimental study

Measurement + Control, 2019
This paper studies the behaviour of circular tunnel subjected to dynamic excitation. Tunnels with three different diameters were selected to perform the shake table test at three different covers. The dry sandy soil was used for testing.
DK Singh, SR Karumanchi, A Mandal, YB Katpatal, A Usmani   +4 more
doaj   +1 more source

Experimental Study of the Engineering Mechanical Properties of the Foundation Soil for Offshore Wind Power Platforms

Shock and Vibration, 2021
Most of the coastal beach zone in the world is rich in wind energy reserves and has great potential for offshore wind power development. However, the sedimentary environment in the coastal area is complex and changeable, and the nature of the foundation ...
Yi Fang, Yuejun Lv, XingYuan Zhou, Yanju Peng   +3 more
doaj   +1 more source

Elastic Parameters of Intermediate Soils Based on Bender-Extender Elements Pulse Tests

Soils and Foundations, 2011
The elastic behaviour of compacted soils subjected to very small strains (smaller than 10 －5) is essential, because the serviceability of most geotechnical structures depends on soil elastic properties. Small-strain stiSness of soils was studied in the past years using diSerent experimental devices (mainly resonant columns).
Murillo, Carol, Sharifipour, Mohammad, Caicedo, Bernardo, Thorel, Luc, Dano, Christophe   +4 more
openaire   +3 more sources

Two-dimensional discrete element modelling of bender element tests on an idealised granular material [PDF]

Granular Matter, 2012
The small-strain (elastic) shear stiffness of soil is an important parameter in geotechnics. It is required as an input parameter to predict deformations and to carry out site response analysis to predict levels of shaking during earthquakes. Bender element testing is often used in experimental soil mechanics to determine the shear (S-) wave velocity ...
O’Donovan, J., O’Sullivan, C., Marketos, G.   +2 more
openaire   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Determination of the force necessary by experiment to bend schedule 40 pipe [PDF]

Científica
The tube bending process consists of plastically deforming the material by applying bending loads to the element until its yielding is overcome. Mechanical bending tests help determine the properties of a material, properties that are used to design the ...
Iván González Uribe, Liliana Gutiérrez Lonche, Romy Pérez Moreno, Ivonne Patricio Macias   +3 more
doaj   +1 more source