Results 31 to 40 of about 112,055 (258)

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

A Sensing Element Based on a Bent and Elongated Grooved Polymer Optical Fiber

open access: yesSensors, 2012
An experimental and numerical investigation is performed into the power loss induced in grooved polymer optical fibers (POFs) subjected to combined bending and elongation deformations. The power loss is examined as a function of both the groove depth and
Wen-Fu Xie   +3 more
doaj   +1 more source

Hollow antiresonant fibers with low bending loss

open access: yesOptics Express, 2014
We first use numerical simulations to show that bending losses of hollow antiresonant fibers are a strong function of their geometrical structure. We then demonstrate this by fabricating a hollow antiresonant fiber which presents a bending loss as low as 0.25 dB/turn at a wavelength of 3.35 μm and a bend radius of 2.5 cm.
Belardi W, Knight JC
openaire   +4 more sources

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur   +5 more
wiley   +1 more source

Analysis of Waveguides on Lithium Niobate Thin Films

open access: yesCrystals, 2018
Waveguides formed by etching, proton-exchange (PE), and strip-loaded on single-crystal lithium niobate (LN) thin film were designed and simulated by a full-vectorial finite difference method.
Yiwen Wang, Zhihua Chen, Hui Hu
doaj   +1 more source

An Ultra-Low Bending Loss Negative Curvature Hollow Core Fiber With a Polygon Jacketing Layer

open access: yesIEEE Photonics Journal, 2023
We design and simulate a new type of hollow-core antiresonant fiber with the polygon jacketing layer. Through numerical calculations, the confinement loss is approximately 0.003 dB/km at 1.45 μm and the bandwidth is ∼ 410 nm @
Yun-Hao Xu   +6 more
doaj   +1 more source

Polarization dependence of bend loss for a standard singlemode fiber [PDF]

open access: yesOptics Express, 2007
Polarization dependence of bend loss caused by the polymer coating layer for a standard singlemode fiber (SMF28) is investigated theoretically and experimentally. Bend loss for SMF28 for both the TE and TM mode is calculated separately. Normalized polarization dependent loss is proposed for the characterization of the polarization sensitivity of bend ...
Wang, Qian   +3 more
openaire   +4 more sources

Current Status and Challenges in Data Collection for Aerospace Coatings Deposited by Plasma Spraying

open access: yesAdvanced Engineering Materials, EarlyView.
An innovative approach has been integrated into the GRENAT project to optimize plasma spraying and coating performance. Raw materials are accelerated and melted in the plasma generated by torches, creating coatings. Monitoring sensors collect process data which are combined with ex situ characterization data.
Lila Randriamananjara   +8 more
wiley   +1 more source

Bend-Net: Bending Loss Regularized Multitask Learning Network for Nuclei Segmentation in Histopathology Images

open access: yesInformation
Separating overlapped nuclei is a significant challenge in histopathology image analysis. Recently published approaches have achieved promising overall performance on nuclei segmentation; however, their performance on separating overlapped nuclei is ...
Haotian Wang   +3 more
doaj   +1 more source

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