Results 31 to 40 of about 181,339 (261)

Adhesive Contact of Nanowire in Three-Point Bending Test

, 2011
A new adhesive receding contact model is presented in this paper for a nanowire in a three-point bending test. Because of its flexability, the nanowire in such a test, may lift-off or separate from its supporting elastic medium; this can dramatically ...
张吟, Zhao, YP (reprint author), Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China, 赵亚溥   +2 more
core   +1 more source

Repeatability of a bending stiffness test for snowboarding wrist protectors [PDF]

, 2023
Snowboarding wrist protectors are typically designed to limit impact forces and prevent wrist hyperextension. The standard for snowboarding wrist protectors (ISO 20320:2020) includes a test for measuring their bending stiffness, when fitted to a wrist ...
Leslie, G, Hamilton, Nick, Wang, W, Hamilton, N., Allen, T., Hamilton, N, Wang, W., Winwood, K, Allen, T, Leslie, G.; id_orcid, Leslie, G., Winwood, K.   +11 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Determination of the force necessary by experiment to bend schedule 40 pipe [PDF]

Científica
The tube bending process consists of plastically deforming the material by applying bending loads to the element until its yielding is overcome. Mechanical bending tests help determine the properties of a material, properties that are used to design the ...
Iván González Uribe, Liliana Gutiérrez Lonche, Romy Pérez Moreno, Ivonne Patricio Macias   +3 more
doaj   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Comparativo da aderência do concreto com aço sem proteção e o aço galvanizado a quente

Revista IBRACON de Estruturas e Materiais
O aumento da vida útil de estruturas é de grande importância para a construção civil, seja por aspectos econômicos quanto de segurança aos usuários. A corrosão de armaduras é um dos problemas mais recorrentes, principalmente em ambientes com alto teor de
B.F. Tutikian, T. Hilgert, J.J. Howland
doaj   +1 more source

Load-carrying capacity of timber-concrete composite panels [PDF]

Инженерно-строительный журнал, 2020
Timber-concrete composite panels, due to its benefits, are one of the most popular alternatives to common slabs of pure timber or concrete. In the analyse of load-carrying capacity for timber-concrete composite panels, subjected to flexure, the important
R. Vasiljevs, D. Serdjuks, K. Buka-Vaivade, A. Podkoritovs, N. Vatin   +4 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Characterizing the bending behavior of underground utility tunnel roofs in a fabricated composite shell system

Frontiers in Materials, 2023
The traditional underground utility tunnel system is characterized by a lengthy construction period, material waste, and poor engineering quality. This study proposes the prefabricated composite shell system underground utility tunnel as a new type of ...
Lei Dong, Lei Dong, Aijun Yao, Daxing Zhou, Daxing Zhou, Pengfei Zhang, Pengfei Zhang   +6 more
doaj   +1 more source