Results 1 to 10 of about 2,472,934 (283)

A practical approach to communicating benefit-risk decisions of medicines to stakeholders [PDF]

Frontiers in Pharmacology, 2015
PurposeThe importance of a framework for a systematic structured assessment of the benefits and risks has been established, but in addition, it is necessary that the benefit-risk decisions and the processes to derive those decisions are documented and ...
James eLeong, Stuart eWalker, Sam eSalek, Sam eSalek   +3 more
doaj   +5 more sources

Integrating environmental effects in the benefit-risk assessment of therapeutic products: a proposal and example for sustainable health and healthcare [PDF]

Frontiers in Drug Safety and Regulation
To mitigate healthcare’s unintended effects, environmental risk data such as ecotoxicity and environmental contamination need to be considered by all stakeholders in the healthcare value chain.
Emiliano Giovagnoni, Luisa Mattoli, Andrea Cossu, Vitalia Murgia   +3 more
doaj   +2 more sources

Patient preferences in the benefit–risk assessment of atopic dermatitis treatments in China: A nationwide surveyCapsule Summary [PDF]

JAAD International
Background: Understanding patient preferences is critical for patient-focused drug development, especially in chronic conditions like atopic dermatitis, where treatment benefit–risk profiles vary widely.
Jingyi Yang, MS, Yang Liu, MD, Hengjing Li, PhD, Yumei Ge, MD, PhD, Chen Yin, PhD, Yun Zhai, MD, PhD, Cong Zhao, MS, Siyuan Qian, MS, Xiaoyuan Chen, PhD, Songmei Xie, MD, PhD   +9 more
doaj   +2 more sources

Patient-based benefit-risk assessment of medicines: development, refinement, and validation of a content search strategy to retrieve relevant studies [PDF]

Journal of the Medical Library Association, 2021
Introduction: Poor indexing and inconsistent use of terms and keywords may prevent efficient retrieval of studies on the patient-based benefit-risk assessment (BRA) of medicines.
Hiba El Masri, Treasure M. McGuire, Christine Dalais, Mieke van Driel, Helen Benham, Samantha A. Hollingworth   +5 more
doaj   +2 more sources

Breastfeeding during infancy and consumption of fish and dairy products are associated with chlorinated persistent organic pollutants in serum from Swedish adolescents

Environmental Advances, 2022
Background: Food is considered the predominant source of human exposure to chlorinated and brominated persistent organic pollutants (POPs). Exposure and potential sources of these compounds are less studied in adolescents.
Galia Zamaratskaia, Helena Bjermo, Anna Karin Lindroos, Päivi Ruokojärvi, Panu Rantakokko, Hannu Kiviranta, Sanna Lignell   +6 more
doaj   +1 more source

The Nordic Nutrition Recommendations 2022 – food consumption and nutrient intake in the adult population of the Nordic and Baltic countries

Food & Nutrition Research, 2022
Background: Knowledge about the nutrient intakes and food consumption in the Nordic and Baltic countries is important for the formulation of dietary reference values (DRVs) and food-based dietary guidelines (FBDGs), as part of the Nordic Nutrition ...
Eva Warensjö Lemming, Tagli Pitsi
doaj   +1 more source

Vitamin D status in children and adults in Sweden: dietary intake and 25-hydroxyvitamin D concentrations in children aged 10–12 years and adults aged 18–80 years

Journal of Nutritional Science, 2020
The study aimed to estimate vitamin D intake and plasma/serum 25-hydroxyvitamin D (25(OH)D) concentrations, investigate determinants of 25(OH)D concentrations and compare two 25(OH)D assays.
Cecilia Nälsén, Wulf Becker, Monika Pearson, Peter Ridefelt, Anna Karin Lindroos, Natalia Kotova, Irene Mattisson   +6 more
doaj   +1 more source

A machine learning approach for identifying variables associated with risk of developing neutralizing antidrug antibodies to factor VIII

Heliyon, 2023
A key unmet need in the management of hemophilia A (HA) is the lack of clinically validated markers that are associated with the development of neutralizing antibodies to Factor VIII (FVIII) (commonly referred to as inhibitors).
Atul Rawal, Christopher Kidchob, Jiayi Ou, Osman N. Yogurtcu, Hong Yang, Zuben E. Sauna   +5 more
doaj   +1 more source

Targeting mitochondrial quality control in muscle aging: Natural dietary products as potential interventions

Food Frontiers, 2023
Mitochondria are the main sources of energy production for muscle tissues, including skeletal, cardiac, or smooth muscle, to support their activities.
Qi Chen, Weisu Huang, Esra Capanoglu, Amel Thanina Amrouche, Baiyi Lu   +4 more
doaj   +1 more source

Low concentrations of perfluoroalkyl acids (PFAAs) in municipal drinking water associated with serum PFAA concentrations in Swedish adolescents

Environment International, 2023
While highly contaminated drinking water (DW) is a major source of exposure to perfluoroalkyl acids (PFAAs), the contribution of low-level contaminated DW (i.e. 
Jennifer Nyström-Kandola, Lutz Ahrens, Anders Glynn, Gunnar Johanson, Jonathan P. Benskin, Irina Gyllenhammar, Sanna Lignell, Carolina Vogs   +7 more
doaj   +1 more source