Results 151 to 160 of about 3,493,028 (307)
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Regulatory Improvement Legislation: Risk Assessment, Cost-Benefit Analysis, and Judicial Review [PDF]
, 2000 Anderson, Fred +3 more
core +1 more source
Assessment Plan and Design: A Model for Enhancing Instruction in Economics Courses [PDF]
This paper develops a systematic approach to course assessment that aims to identify strengths and weaknesses in student achievement and course design that can be addressed through instructional change.
Brian Hill, Jill Caviglia-Harris
core
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Primary endpoint acceptance is strongly associated with a positive benefit assessment: a self-fulfilling prophecy. [PDF]
Lancet Reg Health EurDintsios CM.
europepmc +1 more source
The role and value of water in natural capital restoration on the Agulhas Plain [PDF]
The Agulhas Plain is a low-lying coastal area within the Cape Floristic Region classified as one of the six plant kingdoms of the world. The area is heavily invaded by alien vegetation that infringes upon the sustainable supply of ecosystem goods and ...
Albert van der Merwe +2 more
core
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Application of BRAFO-Tiered Approach for Risk-Benefit Assessment of Nut Consumption in Chinese Adults. [PDF]
FoodsLiu Z +9 more
europepmc +1 more source
Benefit assessment of extended dosing in cancer patients after their withdrawal from clinical trials. [PDF]
Front Pharmacol, 2023 Yang F, Huang Z, Heng J, Li K.
europepmc +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source