Results 181 to 190 of about 3,493,028 (307)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Emergent data influences the risk/benefit assessment of hemophilia gene therapy using recombinant adeno-associated virus. [PDF]

Front Med (Lausanne), 2023
Puetz J.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Optimizing soil conservation through comprehensive benefit assessment in river basins. [PDF]

Environ Sci Ecotechnol
Sun S, Lü Y, Feng X, Maestre FT, Fu B.
europepmc   +1 more source

States of Uncertainty, Risk-Benefit Assessment and Early Clinical Research: A Conceptual Investigation. [PDF]

Sci Eng Ethics, 2022
Schnarr A, Mertz M.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Economic benefits assessment

The document is going to discuss and assess all economic benefits coming from the application of all the proposed aircraft components with integrated ...
openaire   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Risk-benefit assessment of foods and its role to inform policy decisions: outcome of an international workshop. [PDF]

Front Nutr
Matteu Monteiro C, Membré JM, Poulsen M, Thomsen ST, Pires SM.   +4 more
europepmc   +1 more source

Risk-benefit assessment of cold-smoked salmon: microbial risk versus nutritional benefit [PDF]

, 2012
Andersen, Rikke, Berjia, Firew Lemma, Hoekstra, Jeljer, Nauta, Maarten, Poulsen, Morten   +4 more
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