Results 71 to 80 of about 4,574,160 (318)

Delivery of Outpatient Parenteral Antimicrobial Therapy (OPAT) in an Ever-Changing National Health Service (UK): Benefits, Barriers, and Opportunities

Antibiotics
Outpatient parenteral antimicrobial therapy (OPAT) is increasingly used to manage a broad range of infections, enabling patients to receive intravenous antibiotics safely outside inpatient settings.
Oyewole Christopher Durojaiye, Charlotte Fiori, Katharine Cartwright   +2 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

A comparative analysis of the different HIV testing techniques used in Zambia: data from a clinical performance study

BMC Research Notes
Background Approximately 40 million people globally are living with HIV (PLWH) and more than 50% of these PLWH reside in Eastern and Southern Africa. Zambia has an adult HIV-1 prevalence (ages 15–49) of 11.1 [10.5–11.6] %, among the highest in the world (
Loveness Mukuka, Andros Theo, Precious Simushi, Mowa Zambwe, Peter J. Chipimo   +4 more
doaj   +1 more source

Minutes: Benefits Advisory Committee: December 17, 2020

, 2020
Employee Benefits Update; Lutheran Social Services (LSS) Financial Counseling; Employee Assistance Program (EAP) - Sand Creek; Emergency Medical and Travel Assistance Services - RedpointUniversity of Minnesota. Benefits Advisory Committee.
University of Minnesota. Benefits Advisory Committee
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Consumption patterns and attitudinal insights on artificial sweeteners in Saudi Arabia

Frontiers in Public Health
IntroductionArtificial sweeteners (AS) are increasingly used as sugar substitutes in Saudi Arabia, yet no studies have examined the patterns and attitudes related to their consumption.AimTo investigate AS consumption behaviors and attitudes among Saudi ...
Buthaina M. Aljehany, Eman A. Abduljawad, Fadhah Alatwi, Nada Benajiba   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

SOCIAL RESPONSABILITY OF INSURANCE COMPANIES [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2013
The role of corporate social responsibility has increased significantly nowadays. The studies conducted have shown that consumers are increasingly no longer interested only in buying good quality and reliable products, but they are also interested ...
MĂRĂCINE MIHAELA SIMONA
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source