Results 91 to 100 of about 4,574,160 (318)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Bulletin of the Transilvania University of Braşov: Series IX Sciences of Human KineticsThe scientific research on using CrossFit in combat sports like judo and sambo lacks evidence, prompting further investigation. This paper aims to analyze existing literature on CrossFit and combat sports.
C. Stanciu, V. Ene-Voiciulescu
doaj +1 more source
Minutes: Benefits Advisory Committee: September 17, 2020
, 2020 University of Minnesota. Benefits Advisory Committee. (2020). Minutes: Benefits Advisory Committee: September 17, 2020.
University of Minnesota. Benefits Advisory Committee
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FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
AgricultureCover crops are becoming widely integrated into many farms as tools for improving sustainability. However, the decisions by growers for planting follow several objectives/criteria, many of which overlap.
Paul Cottney +3 more
doaj +1 more source
State support of small business: a modern practice in Russia and abroad
Ученые записки Российской академии предпринимательства, 2021 The article deals with a topical theme of state support of the small business organizations. This article analyzes the system of support activities and small business development in Russia and abroad. Conclusions and proposals to support small businesses
V. B. Frolova, A. K. Margaryan
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
La certification qualité en milieu rural comme moteur de viabilité du tourisme
Téoros, 2020 One of the main pillars of sustainable rural tourism is the economic viability of businesses. The rural quality certification can be an interesting instrument to evaluate it, given that it has positive direct and indirect effects on sustainability, by ...
Francisco Javier de la Ballina +2 more
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How India implements social policy
Ученые записки Российской академии предпринимательства, 2021 The article discusses the current situation in India in the field of social policy, which has been reviewed and analyzed. The caste structure of society in the country plays a negative role for its economy and society.
G. .. Sharma
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