Results 81 to 90 of about 4,574,160 (318)
The Impact of Covid-19 Pandemic on Students’ Sport Activity
The rapid spread of COVID-19 virus in Romania has had a substantial impact on higher education, where almost all institutions have been closed and on-site teaching activities have been replaced by online courses (at the peak of the pandemic, 90% of the ...
Cristian-Ioan ȘANTA-MOLDOVAN +4 more
doaj +1 more source
TOURISM AN IMPORTANT SECTOR OF ECONOMY DEVELOPMENT [PDF]
Tourism has become an important sector that has an impact on development of country economy. The main benefits of tourism are income creation and generation of jobs. For many regions and countries it is the most important source of welfare.
Xhiliola Agaraj, Merita Murati
doaj
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
BENEFITS, COSTS AND LIMITS OF ECONOMIC INCREASE [PDF]
The macroeconomic situation of a nation cannot be characterized just by the equilibrium conditions of its economy, but especially by the growth level and rate of the gross domestic product or the national, total income and per inhabitant.
VĂDUVA CECILIA ELENA
doaj
Minutes: Benefits Advisory Committee: October 15, 2020
In these minutes: Employee Benefits Update; Cancer Issues in the UPlan; Minnesota Cancer Alliance - Cancer Plan 2025; Masonic Cancer Center - Cancer 101; Discuss Employee Survey from BAC and BAC Vice Chair Election Schedule; Review BAC ChargeUniversity ...
University of Minnesota. Benefits Advisory Committee
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
At present, ChatGPT is penetrating all spheres of human activities, and especially education is no exception. The purpose of this exploratory study is to examine the potentials and pitfalls of using ChatGPT for academic purposes among university students,
Blanka Klimova +1 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

