Results 31 to 40 of about 1,605,836 (247)

Morphological Pattern of Benign Skin Tumors in a Teaching Hospital in Southeast Nigeria [PDF]

Background: Benign skin tumors are non-malignant neoplasms of skin origin. They are not uncommon and some have the dreaded propensity for malignant transformation.
Samuel Uchechukwu Okparaoka, Amobi Chiedozie Oguonu, Amaechi Ugbala, Ugochukwu Uzodimma Nnadozie, Charles Chidebele Maduba, Aloysius Ugwu-Olisa Ogbuanya, Uche Valentine Okeke   +6 more
core   +1 more source

Chondromas and multiple enchondromatosis

Гений oртопедии, 2021
Introduction The chondromas are a cartilaginous proliferation of mature appearance and moderate size, reason why these tumors are regarded more like hamartomas than real benign tumor. Chondromas represent 10 to 12 % of benign bone tumors. Any bone of an
Pierre Lascombes, Laurence Mainard-Simard   +1 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

A rare location for a common bone tumor, meta-diaphyseal giant cell tumor of bone in an adult patient

Rare Tumors, 2013
Primary bone tumors can be either benign or malignant considering their natural history and cellular morphology. Benign bone tumors are much more frequent than malignant ones although some of them like giant cell tumor of bone can behave just like a ...
Darioush M. Barzi, Sam H. Sámi, Ehsan Fallah   +2 more
doaj   +1 more source

A molecular map of mesenchymal tumors [PDF]

, 2005
Background: Bone and soft tissue tumors represent a diverse group of neoplasms thought to derive from cells of the mesenchyme or neural crest. Histological diagnosis is challenging due to the poor or heterogenous differentiation of many tumors, resulting
Flanagan, AM, Guiliano, D, Boshoff, C, McLean, S, Frow, R, Sebire, N, Henderson, SR, Stephen R Henderson, Nick Athanasou, Vujovic, S, Anderson, J, Athanasou, N, John Anderson, Neil Sebire, David Guiliano, Sean McLean, Nadege Presneau, Richard Frow, Jeremy Whelan, Whelan, J, Adrienne M Flanagan, Presneau, N, Sonja Vujovic, Chris Boshoff   +23 more
core   +1 more source

Evaluation of the expression pattern and diagnostic value of PPARγ in malignant and benign primary bone tumors

BMC Musculoskeletal Disorders, 2022
Purpose The quantifiable description of PPARγ expression pattern beside mechanistic in-vitro evidence will provide insights into the involvement of this mediator in tumor pathogenesis.
Amir Reza Eghtedari, Mohammad Amin Vaezi, Banafsheh Safizadeh, Ghasem Ghasempour, Pegah Babaheidarian, Vahid Salimi, Masoumeh Tavakoli-Yaraki   +6 more
doaj   +1 more source

Percutaneous Treatments of Benign Bone Tumors [PDF]

Seminars in Interventional Radiology, 2018
AbstractBenign bone tumors consist of a wide variety of neoplasms that do not metastasize but can still cause local complications. Historical management of these tumors has included surgical treatment for lesion resection and possible mechanical stabilization. Initial percutaneous ablation techniques were described for osteoid osteoma management.
Koch, Guillaume, Cazzato, Roberto Luigi, Gilkison, Andrew, Caudrelier, Jean, Garnon, Julien, Gangi, Afshin   +5 more
openaire   +3 more sources

RGS16 Aggravates Hepatic Ischemia‐Reperfusion Injury via Hepatocyte‐Intrinsic Apoptosis/Inflammation & Neutrophil Recruitment/NETosis

Advanced Science, EarlyView.
RGS16 competitively interferes with the YTHDF3–PAN3 complex to prevent CXCL1 mRNA decay during hepatic ischemia‐reperfusion injury. Stabilized CXCL1 strengthens hepatocyte injury, neutrophil recruitment, and NET‐associated inflammation, uncovering how stress‐induced RGS16 converts post‐transcriptional regulation into immune‐mediated liver damage ...
Xinglong Li, Zhanzhi Meng, Hongjun Yu, Yongliang Hua, Zihao Li, Bing Yin, Baolin Qian, Zhongyu Li, Yongzhi Zhou, Zhigang Feng, Shounan Lu, Shanjia Ke, Miaoyu Bai, Yao Fu, Wei Tang, Natalia V. Belosludtseva, Yong Ma   +16 more
wiley   +1 more source