Results 1 to 10 of about 2,694,526 (308)

Nomogram for Predicting the Postoperative Venous Thromboembolism in Spinal Metastasis Tumor: A Multicenter Retrospective Study

Frontiers in Oncology, 2021
IntroductionVenous thromboembolism can be divided into deep vein thrombosis and pulmonary embolism. These diseases are a major factor affecting the clinical prognosis of patients and can lead to the death of these patients.
Hao-ran Zhang, Ming-you Xu, Xiong-gang Yang, Feng Wang, Hao Zhang, Li Yang, Rui-qi Qiao, Ji-kai Li, Yun-long Zhao, Jing-yu Zhang, Yong-cheng Hu   +10 more
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MicroRNA‐215‐5p promotes proliferation, invasion, and inhibits apoptosis in liposarcoma cells by targeting MDM2

Cancer Medicine, 2023
Background Liposarcoma (LPS) is one of the most common soft tissue malignancies in adults, and it is characterized by dysregulation of multiple signaling pathways, including MDM2 proto‐oncogene (MDM2) amplification.
Zhengnan Song, Jingping Bai, Renbing Jiang, Junshen Wu, Wenpeng Yang   +4 more
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METTL3 stabilizes HDAC5 mRNA in an m6A-dependent manner to facilitate malignant proliferation of osteosarcoma cells

Cell Death Discovery, 2022
Osteosarcoma (OS) is a prevalent primary bone sarcoma. Methyltransferase-like 3 (METTL3) is dysregulated in human malignancies. This study explored the mechanism of METTL3 in OS cell proliferation.
Renbing Jiang, Zhibing Dai, Junshen Wu, Suzhi Ji, Yachao Sun, Wenpeng Yang   +5 more
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Reprogramming tumor microenvironment via dual targeting co-delivery of regorafenib and alpha-difluoromethylornithine in osteosarcoma

Cancer Nanotechnology, 2023
Background Tumor angiogenesis, immunosuppression, and progression are all closely correlated with the tumor microenvironment (TME). Immune evasion is supported by both M2 phenotype tumor-associated macrophages (TAMs) and vascular aberrations in the TME ...
Hongsheng Wang, Xinmeng Jin, Yinghua Gao, Xin He, Yiming Xu, Haoran Mu, Yafei Jiang, Zhuoying Wang, Chen Yu, Tao Zhang, Yingqi Hua, Zhengdong Cai, Jing Xu, Xiaojun Ma, Wei Sun   +14 more
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Withaferin A inhibits osteosarcoma cells through inactivation of Notch-1 signalling

Bangladesh Journal of Pharmacology, 2014
Human osteosarcoma cells were treated with withaferin A and the antiproliferative activity was evaluated by the 3-(4, 5 dimethyl-thiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assays.
Yang Chen, Xiang-Zhen Han, Wei Wang, Ren-Tao Zhao, Xiao Li   +4 more
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Resection and reconstruction of huge tumors in the chest wall

Journal of Cardiothoracic Surgery, 2022
Objective To evaluate the experience and effects of resection and reconstruction of 4 cases of huge tumors in the chest wall. Methods The clinical data of 4 patients with huge tumors in the chest wall from July 2015 to January 2020 were collected and ...
Zhibing Dai, Maierdanjiang Maihemuti, Yachao Sun, Renbing Jiang   +3 more
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MYLK4 promotes tumor progression through the activation of epidermal growth factor receptor signaling in osteosarcoma

Journal of Experimental & Clinical Cancer Research, 2021
Background Osteosarcoma (OS) is the most common primary bone cancer in adolescents and lung metastasis is the leading cause of death in patients with OS. However, the molecular mechanisms that promote OS growth and metastasis remain unknown.
Mengkai Yang, Tao Zhang, Yangfeng Zhang, Xiaojun Ma, Jing Han, Ke Zeng, Yafei Jiang, Zongyi Wang, Zhuoying Wang, Jing Xu, Yingqi Hua, Zhengdong Cai, Wei Sun   +12 more
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CircDOCK1 promotes the tumorigenesis and cisplatin resistance of osteogenic sarcoma via the miR-339-3p/IGF1R axis

Molecular Cancer, 2021
Background Circular RNAs (circRNAs), a class of noncoding RNAs (ncRNAs), may modulate gene expression by binding to miRNAs. Additionally, recent studies show that circRNAs participate in some pathological processes.
Shenglong Li, Fei Liu, Ke Zheng, Wei Wang, Enduo Qiu, Yi Pei, Shuang Wang, Jiaming Zhang, Xiaojing Zhang   +8 more
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Influence of neoadjuvant chemotherapy on prognosis of patients with synovial sarcoma

World Journal of Surgical Oncology, 2017
Background This study aimed to explore the clinical efficacy of neoadjuvant chemotherapy combined with surgery in primary synovial sarcoma of the limbs and trunk through retrospective analysis of patients with primary synovial sarcoma of the limbs and ...
Yanan Wu, Wenzhi Bi, Gang Han, Jinpeng Jia, Meng Xu   +4 more
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Postoperative Functional Assessment in Patients with Tumors Around the Knee Treated with Endoprosthetic Reconstruction: A Multicenter Retrospective Cohort Study

Technology in Cancer Research & Treatment, 2023
Objectives The restoration of as much normal function as possible has become an important goal following the endoprosthetic reconstruction. The objective of this study was to assess the functional outcome after endoprosthetic reconstruction for tumors ...
Yun-long Zhao MD, Hao-ran Zhang MD, Jing-yu Zhang MD, Yong-cheng Hu MD, PhD   +3 more
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