Results 41 to 50 of about 2,694,526 (308)

Applications and Future Prospects of Micro/Nanorobots Utilizing Diverse Biological Carriers

Micromachines, 2023
Targeted drug delivery using micro-nano robots (MNRs) is a rapidly advancing and promising field in biomedical research. MNRs enable precise delivery of drugs, addressing a wide range of healthcare needs.
Yu Lv, Ruochen Pu, Yining Tao, Xiyu Yang, Haoran Mu, Hongsheng Wang, Wei Sun   +6 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Causal Associations of Inflammatory Cytokines With Osteosarcopenia: Insights From Mendelian Randomization and Single Cell Analysis

Mediators of Inflammation
Conclusion: This study offers preliminary insights into the inflammatory mechanisms potentially driving osteosarcopenia, identifying key cytokines that may be involved in its pathogenesis.
Zugui Wu, Jiyong Yang, Yue Zhu, Jiao Li, Kang Xu, Yuanlong Li, Guoqing Zhong, Yanfei Xu, Ying Guo, Yu Zhang   +9 more
doaj   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Injectable Tumor Microenvironment-Modulated Hydrogels with Enhanced Chemosensitivity and Osteogenesis for Tumor-Associated Bone Defects Closed-Loop Management

, 2022
Patients with postoperative tumor-associated bone defects need both chemotherapy and bone repair in the shifted disease states, but chemotherapy resistance, severe side-effects, and poor bone regeneration result in tumor recurrence and therapy failure ...
Cai, Min, Crawford, Ross William, Zhou, Shiqi, Wang, Le, Ning, Chengyun, Huang, Jingyan, Xiao, Yin, Wang, Yan, Lee, Yichen, Fan, Lei, Zhou, Lei, Yang, Bo, Li, Xiaojun, Xiao, Cairong, Xu, Meng   +14 more
core   +1 more source

Mid- to long-term effects of two different biological reconstruction techniques for the treatment of humerus osteosarcoma involving caput humeri

World Journal of Surgical Oncology, 2020
Background The proximal humerus is one of the most common sites of primary or metastatic malignant tumors. Reconstruction of the shoulder after tumor resection is controversial and challenging.
Weitao Yao, Qiqing Cai, Jiaqiang Wang, Jingyu Hou   +3 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

An innovative staged prosthetic lengthening reconstruction strategy for osteosarcoma-related leg discrepancy

Scientific Reports
Correction of leg length discrepancy (LLD) in skeletally mature patients with osteosarcoma was rarely reported and quite challenging. This study aimed to propose a treatment strategy of staged lengthening and reconstruction with a standard static ...
Hairong Xu, Yuan Li, Feng Yu, Weifeng Liu, Lin Hao, Qing Zhang, Xiaohui Niu   +6 more
doaj   +1 more source

Phase II trial of VEGFR2 inhibitor apatinib for metastatic sarcoma: focus on efficacy and safety

Experimental and Molecular Medicine, 2019
Cancer: Starving sarcomas into submission A drug that inhibits blood vessel growth offers a potentially promising treatment for a class of tumors with a poor prognosis.
Zhichao Liao, Feng Li, Chao Zhang, Lei Zhu, Yehui Shi, Gang Zhao, Xu Bai, Shafat Hassan, Xinyue Liu, Ting Li, Peipei Xing, Jun Zhao, Jin Zhang, Ruwei Xing, Sheng Teng, Yun Yang, Kexin Chen, Jilong Yang   +17 more
doaj   +1 more source

Benign Bone Tumors

Radiologic Clinics of North America, 2011
A solid knowledge of underlying histopathology of benign bone tumors aids in differential diagnoses of these tumors. Important factors in diagnosis of a bone tumor include patient age and gender; the bone involved; the location of the tumor along, within, or on the bone; lesion margin; matrix proliferation; and periosteal reaction.
Motamedi, Kambiz, Seeger, Leanne L
openaire   +4 more sources