Results 21 to 30 of about 2,694,526 (308)

Clinical relevance of circulating tumour cells in the bone marrow of patients with SCCHN [PDF]

, 2004
Background: Clinical outcome of patients with head and neck squamous cell carcinoma (SCCHN) depends on several risk factors like the presence of locoregional lymph node or distant metastases, stage, localisation and histologic differentiation of the ...
Walz, A., Kolbow, K., Chaubal, S., Pauli, C., Andratschke, M., Wollenberg, Barbara   +5 more
core   +1 more source

Engineering the tumor microenvironment of colorectal cancer [PDF]

, 2014
The tumor microenvironment contributes significantly to the clinical prognosis, especially in CRC. Infiltration by cells from the adaptive immune system (e.g. CD8) has been linked to a better survival independently of TNM-stage.
Hirt, Christian Kurt
core   +1 more source

Time and dose dependency of bone-sarcomas in patients injected with radium-224 [PDF]

, 1988
The time course and dose dependency of the incidence of bone-sarcomas among 900 German patients treated with high doses of radium-224 is analysed in terms of a proportional hazards model with a log-normal dependency of time to tumor and a linear ...
Land, C.E., Kellerer, Albrecht M., Mays, C.W., Chmelevsky, D., Spiess, H., Land, C. E., Kellerer, A.M., Mays, C. W., Spieß, H.F., H. Spiess, D. Chmelevsky, C. W. Mays, C. E. Land, A. M. Kellerer   +13 more
core   +1 more source

Bone-targeted nanoplatform enables efficient modulation of bone tumor microenvironment for prostate cancer bone metastasis treatment

, 2022
As there is currently no effective therapy for patients with prostate cancer (PCa) bone metastasis, it was stringent to explore the relevant treatment strategies.
Tingting Zhang (264633), Jingwen Huang (232382), Hui Wang (30400), Shulong Jiang (4686271), Qingbin Liu (210724), Lu Yao (444605), Xiangyu Zhang (630437), Pei Gao (706102)   +7 more
core   +1 more source

Anlotinib Reverses Multidrug Resistance (MDR) in Osteosarcoma by Inhibiting P-Glycoprotein (PGP1) Function In Vitro and In Vivo

Frontiers in Pharmacology, 2022
Overexpression of the multidrug resistance (MDR)-related protein P-glycoprotein (PGP1), which actively extrudes chemotherapeutic agents from cells and significantly decreases the efficacy of chemotherapy, is viewed as a major obstacle in osteosarcoma ...
Gangyang Wang, Gangyang Wang, Lingling Cao, Yafei Jiang, Yafei Jiang, Tao Zhang, Tao Zhang, Hongsheng Wang, Hongsheng Wang, Zhuoying Wang, Zhuoying Wang, Jing Xu, Jing Xu, Min Mao, Min Mao, Yingqi Hua, Yingqi Hua, Zhengdong Cai, Zhengdong Cai, Xiaojun Ma, Xiaojun Ma, Shuo Hu, Shuo Hu, Chenghao Zhou, Chenghao Zhou   +24 more
doaj   +1 more source

Thermoablation of Bone Tumors [PDF]

RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 2016
The aim of this article is to review the significance of percutaneous thermal ablation in the treatment of bone tumors. We describe available ablation techniques as well as advantages and disadvantages in specific settings. In detail, radiofrequency ablation (RFA), microwave ablation (MWA), laser ablation, high intensity focused ultrasound (HIFU) and ...
K I, Ringe, M, Panzica, C, von Falck
openaire   +2 more sources

Liquid-liquid phase separation drives immune signaling transduction in cancer: a bibliometric and visualized study from 1992 to 2024

Frontiers in Oncology
BackgroundLiquid–liquid phase separation (LLPS) is a novel concept that could explain how living cells precisely modulate internal spatial and temporal functions.
Yanhong Pei, Haijie Liang, Yu Guo, Boyang Wang, Han Wu, Zhijian Jin, Shanyi Lin, Fanwei Zeng, Yifan Wu, Qianyu Shi, Jiuhui Xu, Yi Huang, Tingting Ren, Jiarui Liu, Jiarui Liu, Wei Guo   +15 more
doaj   +1 more source

The prognostic value of C-X-C motif chemokine receptor 4 in patients with sporadic malignant peripheral nerve sheath tumors

Chinese Journal of Cancer, 2017
Background Recent studies indicate that C-X-C motif chemokine receptor 4 (CXCR4) and its ligand, C-X-C motif chemokine ligand 12 (CXCL12), stimulate expression of the cell cycle regulatory protein Cyclin D1 in neurofibromatosis 1-associated malignant ...
Chao Zhang, Fang-Yuan Chang, Wen-Ya Zhou, Ji-Long Yang   +3 more
doaj   +1 more source

Treatment of Bone Tumors [PDF]

Surgical Pathology Clinics, 2012
In this article, the authors summarize the state of the art and future potential in the management of Osteosarcoma, Ewing's sarcoma, and Chondrosarcoma. They cover systemic therapy, surgical therapy, and radiotherapy, along with targeted therapies to inhibit signal transduction pathways.
Rajiv, Rajani, C Parker, Gibbs
openaire   +2 more sources

The role of mesh technology with tumor prosthesis reconstruction to reconstruct the extensor mechanism of knee joint after resection of proximal tibial tumors

Journal of Orthopaedic Surgery and Research, 2019
Purpose The aim of this study was to evaluate the role of mesh technique in the reconstruction of the extensor mechanism after resection of proximal tibial tumors.
Bin Liu, Jia Chang Tan, Hui Lin Wang, Zhenjie Wu, Zhen Chao Yuan, Chang Yuan Wei   +5 more
doaj   +1 more source