Results 91 to 100 of about 143,948 (293)

Effect of aging on endogenous level of 5 alpha-dihydrotestosterone, testosterone, estradiol, and estrone in epithelium and stroma of normal and hyperplastic human prostate. [PDF]

, 1993
associated with aging. Thus, the question arises whether or not a correlation exists between the well known prostatic androgen and estrogen accumulation and aging.
Krieg, Michael, Nass, Ralf, Tunn, Sabine
core   +1 more source

The global burden of lower urinary tract symptoms suggestive of benign prostatic hyperplasia: A systematic review and meta-analysis

Scientific Reports, 2017
Benign prostatic hyperplasia is a common non-malignant condition among older men, but the epidemiology is poorly characterised. We summarised and determined the global prevalence of benign prostatic hyperplasia.
Shaun Wen Huey Lee, E. Chan, Y. K. Lai
semanticscholar   +1 more source

Activation of PI3K and deletion of p53 in keratin 15‐expressing mouse mammary cells induces tumor heterogeneity and plasticity modeling metaplastic breast cancer

The Journal of Pathology, EarlyView.
Abstract Although relatively rare, metaplastic breast cancer responds poorly to traditional therapies compared to other subtypes. Accordingly, there is a need for novel animal models to understand its pathogenesis and plasticity. Since alterations in PIK3CA and TP53 genes are common in metaplastic breast cancer, we generated a mouse model of ...
Khoa A Nguyen, Lauren E McLemore, Yao Ke, Lisa N DePledge, Lynelle P Smith, Li Bian, John D Aleman, David Debretsion, Erica Wong, Nicole Manning, Xiao‐Jing Wang, Christian D Young   +11 more
wiley   +1 more source

Tamsulosin � turn a round [PDF]

, 2011
Tamsulosin is a sulfamoylphen-ethylamine derivative, a potent and a selective antagonist of Alpha-1A adrenoceptor. It s approved in the treatment of LUTS in BPH disease, being a specific Alpha -1A blocker it does not interfere much with the ...
Praveen R, Int J Cur Bio Med Sci.
core  

Functional role and tobacco smoking effects on methylation of CYP1A1 gene in prostate cancer. [PDF]

, 2016
Cytochrome P450 (CYP) 1A1 is a phase I enzyme that can activate various compounds into reactive forms and thus, may contribute to carcinogenesis. In this study, we investigated the expression, methylation status, and functional role of CYP1A1 on prostate
Chang, Inik, Dahiya, Rajvir, Deng, Guoren, Fukuhara, Shinichiro, Hashimoto, Yutaka, Imai-Sumida, Mitsuho, Kato, Taku, Majid, Shahana, Mitsui, Yozo, Nakajima, Koichi, Saini, Sharanjot, Shiina, Hiroaki, Shiina, Marisa, Tanaka, Yuichiro, Wong, Darryn K, Yamamura, Soichiro   +15 more
core   +1 more source

Widespread Skin Telangiectasias in Spinocerebellar Ataxia Type 27B

Annals of Neurology, EarlyView.
Victor Alm, Håkan Thonberg, Per Svenningsson, Martin Paucar   +3 more
wiley   +1 more source

Altered Glycosylation of PSA in Prostate Cancer Tissue

The Prostate, EarlyView.
ABSTRACT Background The glycosylation of proteins is commonly altered in cancer. This offers novel opportunities for cancer biomarker development. As prostate‐specific antigen (PSA) is a glycoprotein, identification of cancer‐specific PSA‐glycoforms is feasible. Such PSA‐glycoforms may provide valuable diagnostic and prognostic information. Methods PSA‐
Hannu Koistinen, Ruusu‐Maaria Merivirta, Timo‐Pekka Lehto, Anna Lempiäinen, Andrew Erickson, Ulf‐Håkan Stenman, Antti Rannikko, Tuomas Mirtti   +7 more
wiley   +1 more source

Improving Patient Decision-Making in Health Care [PDF]

, 2011
Outlines regional variations within Minnesota in rates of patients with similar conditions receiving elective surgery, the concept of shared decision making, treatment choices for eight conditions, and steps for ensuring patients make informed ...
David C. Goodman, Elliott S. Fisher, John E. Wennberg, Julie P. W. Bynum, Michael J. Barry, Shannon Brownlee   +5 more
core  

Magnitude and factors associated with benign prostatic hyperplasia among adult male patients visiting Wolaita Sodo University comprehensive specialized hospital southern Ethiopia

Scientific Reports
Worldwide, in Africa and Ethiopia prevalence of Benign Prostatic Hyperplasia among patients with lower urinary tract symptoms was 26.2%, 44.2%, and 33.4% respectively.
Tirufat Tiruneh, Tamiru Getachew, Firdawek Getahun, Tesfaye Gebreyesus, Simeon Meskele   +4 more
doaj   +1 more source

Is There Any Association Between Periodontitis and Prostatic Alterations? A Systematic Review

The Prostate, EarlyView.
ABSTRACT Background The prostate plays a crucial role in male reproduction but is susceptible to diseases such as prostate cancer. Periodontitis, as an inflammatory disease, has the potential to modulate systemic conditions. This systematic review aimed to evaluate the association between periodontitis and prostatic alterations.
Beatriz Rodrigues Risuenho Peinado, Rayssa Maitê Farias Nazário, Deborah Ribeiro Frazão, Yago Gecy de Sousa Né, Leonardo Oliveira Bittencourt, Nathália Carolina Fernandes Fagundes, Caio Melo Mesquita, Cassiano Kuchenbecker Rösing, Renata Duarte de Souza‐Rodrigues, Luiz Renato Paranhos, Lucianne Cople Maia, Rafael Rodrigues Lima   +11 more
wiley   +1 more source