Results 101 to 110 of about 151,271 (335)

Unraveling the Metabolic Influence of Olfactory Receptors in Cancer Cells

Sensory Neuroscience, EarlyView.
ORs are aberrantly expressed in various tumor types and regulate cancer cell metabolism through nonclassical signaling pathways, including PI3K/Akt, MAPK, and ERK. These receptors influence tumor proliferation, invasion, and immune evasion. Specific OR–ligand interactions offer promising opportunities for targeted cancer therapy and early diagnosis ...
Chengzhilin Li, Xiaochen Gao, Ziheng Liu, Nianlei Zhang, Xue Cao, Wenwen Qi, Chengcheng Liu   +6 more
wiley   +1 more source

Magnitude and factors associated with benign prostatic hyperplasia among adult male patients visiting Wolaita Sodo University comprehensive specialized hospital southern Ethiopia

Scientific Reports
Worldwide, in Africa and Ethiopia prevalence of Benign Prostatic Hyperplasia among patients with lower urinary tract symptoms was 26.2%, 44.2%, and 33.4% respectively.
Tirufat Tiruneh, Tamiru Getachew, Firdawek Getahun, Tesfaye Gebreyesus, Simeon Meskele   +4 more
doaj   +1 more source

Improving Patient Decision-Making in Health Care [PDF]

, 2011
Outlines regional variations within Minnesota in rates of patients with similar conditions receiving elective surgery, the concept of shared decision making, treatment choices for eight conditions, and steps for ensuring patients make informed ...
David C. Goodman, Elliott S. Fisher, John E. Wennberg, Julie P. W. Bynum, Michael J. Barry, Shannon Brownlee   +5 more
core  

Silodosin oral films: Development, physico-mechanical properties and in vitro dissolution studies in simulated saliva [PDF]

, 2019
Sublingual film dosage forms for drugs used for fast symptomatic treatment have promise because they allow a rapid onset of action. The aim of this study was to prepare films of silodosin intended for sublingual administration for the symptomatic ...
Adair, Alhayali, Allam, Alonzo, Boateng, Brady, Brouwers, Campisi, Chapple, Curatolo, De Caro, El-Setouhy, ElMeshad, Gao, Garsuch, Gittings, Guo, Hanif, Hobbs, Huang, Humphrey, Jug, Kalia, Kapoor, Kim, Koland, Korhonen, Li, Liew, Madhav, Mashru, Matsubara, Miller-Chou, Montorsi, Nagy, Patel, Prabhu, Prasad, Preis, Preis, Preis, Radebaugh, Repka, Rossi, Runja, Sharma, Singh, Singh, Singh, Singh, Slavkova, Tanno, Vila, Visser, Vuddanda, Vuddanda, Yang, Zhang   +57 more
core   +2 more sources

Effect of combination treatment on patient-related outcome measures in benign prostatic hyperplasia: clinical utility of dutasteride and tamsulosin

Patient Related Outcome Measures, 2011
Bob Djavan, Seyed Saeid Dianat, Amir KazzaziNew York University, Department of Urology, New York, USABackground: Benign prostatic hyperplasia, the fourth most commonly diagnosed medical condition in the elderly, is a major underlying cause of lower ...
Djavan B, Dianat SS, Kazzazi A
doaj  

Pterostilbene Effect on Inflammatory and Oxidation Markers in Benign Prostatic Hyperplasia Rats Model

Iraqi Journal of Pharmaceutical Sciences
Pterostilbene is a potent anti-inflammatory and antioxidant used to treat benign prostatic hyperplasia, which is brought on by the induction of testosterone propionate.
Mohammed Ridha Jawad, Ghaith Ali Jasim
doaj   +1 more source

Unveiling the potential of emerging microRNA panels as diagnostic biomarkers for prostate cancer: A review

UroPrecision, EarlyView.
Abstract Prostate cancer (PCa) is a multifaceted disease that envelops 1.41 million new cases globally. It is the second most common cancer reported in men. Its heterogeneity and indolent growth, coupled with incompetent early screening methods such as serum prostate‐specific antigen level estimations and digital rectal examinations, contribute to its ...
Anveshika Manoj, Gautam Prasad, Mohammad Kaleem Ahmad   +2 more
wiley   +1 more source

Assessing the utility of a natural language processing model in answering common urological questions

UroPrecision, EarlyView.
ABSTRACT Background ChatGPT, an interactive natural language processing model, is becoming increasingly used for medical information gathering. The objective of this study is to investigate the appropriateness of ChatGPT's responses to common urological questions compared to the Canadian Urological Association (CUA) guideline recommendations. Methods A
Wyatt MacNevin, John‐David Brown, Nicholas Dawe, Jesse T. R. Spooner, Nicholas R. Paterson, Daniel T. Keefe, David G. Bell   +6 more
wiley   +1 more source

Prostate blood flow in patients with benign prostatic hyperplasia complicated by urine retention

RUDN Journal of Medicine, 2012
Benign prostatic hyperplasia is the most frequent disease among middle and old aged men and connected with increasing of lifetime of men. The incidence of the disease is 42% to 87% in different aged groups.
E A Atamanova, V P Avdoshin, M I Andryukhin, V V Chugaev   +3 more
doaj  

TRANSCRIPTION FACTOR BRN-3α AND PROSTATE CANCER, RELATION WITH HORMONE RECEPTORS AND AKT/M-TOR SIGNALING PATHWAY ACTIVATION

Сибирский онкологический журнал, 2018
Introduction. The transcription factor Brn-3α (product of the POU4F1) plays a significant role in carcinogenesis. The purpose of the study was to investigate Brn-3α, AR, ERα expressions in tissues of benign prostatic hyperplasia and prostate cancer as ...
L. V. Spirina, A. K. Gorbunov, I. V. Kondakova, E. M. Slonimskaya, E. A. Usynin   +4 more
doaj   +1 more source