Results 31 to 40 of about 4,248 (155)

Mild intrahepatic cholestasis of pregnancy—A call to redefine diagnostic criteria and consider a new management paradigm

open access: yes
Pregnancy, Volume 2, Issue 1, January 2026.
Minhazur Sarker   +9 more
wiley   +1 more source

Engineering a Human‐Sized Common Bile Duct Prototype with Regenerative Potential: In Vitro Evaluation of Mechanics, Function, Degradation, and Immune Modulation

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 21, August 19, 2025.
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua   +9 more
wiley   +1 more source

The debut of benign recurrent intrahepatic cholestasis in acute hepatitis A [PDF]

open access: yes
Background. Benign recurrent intrahepatic cholestasis is a rare inherited disorder characterized by recurrent episodes of severe hyperbilirubinemia and pruritus that resolve spontaneously.
A. O. Grigorevskaya   +4 more
core   +2 more sources

Odevixibat for Episodic Intrahepatic Cholestasis due to Biallelic Mutations in ATP8B1: A Case Series

open access: yesLiver International, Volume 45, Issue 8, August 2025.
ABSTRACT Background & Aims In episodic intrahepatic cholestasis (IC; known historically as benign recurrent intrahepatic cholestasis), intermittent cholestasis is typically followed by periods of remission. During cholestatic episodes, symptoms can include jaundice, fatigue, abdominal pain, diarrhoea, and severe pruritus that can interfere with ...
Angelo Di Giorgio   +9 more
wiley   +1 more source

IgG4‐Related Disease Mimicking Metastatic Malignancy: Polyserositis and Abdominal Lymphadenopathy

open access: yesClinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT In patients presenting with multiple space‐occupying lesions, preserved general condition, and normal or mildly elevated tumor markers, IgG4‐related disease (IgG4‐RD) should be considered in the differential diagnosis. We report an extremely unusual case of IgG4‐RD mimicking metastatic malignancy, with polyserositis and widespread abdominal ...
Meisi Huo   +3 more
wiley   +1 more source

Endoscopic management of primary sclerosing cholangitis

open access: yesDigestive Endoscopy, Volume 37, Issue 7, Page 723-732, July 2025.
Primary sclerosing cholangitis (PSC) is a progressive autoimmune hepatobiliary disease characterized by fibrotic strictures in the bile ducts, leading to chronic cholestasis and cirrhosis. Magnetic resonance cholangiopancreatography (MRCP) is a noninvasive method for evaluating the condition of the bile ducts, and has high sensitivity and specificity ...
Suguru Mizuno   +8 more
wiley   +1 more source

Use of a Modified Transhepatic Rendezvous Technique for Stenting of Malignant Biliary Obstruction in 2 Cats

open access: yesJournal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT We describe the successful treatment of biliary duct obstruction (BDO) secondary to biliary carcinoma involving the bile duct, cystic duct, and intrahepatic ducts in two adult domestic shorthair cats using a novel technique. Both cats presented with marked hyperbilirubinemia, increased liver enzyme activities, and ultrasonographic evidence of ...
Robin Doherty   +2 more
wiley   +1 more source

Interventions for treating cholestasis in pregnancy (Review) [PDF]

open access: yes, 2013
BACKGROUND: Obstetric cholestasis has been linked to adverse maternal and fetal/neonatal outcomes. As the pathophysiology is poorly understood, therapies have been empiric.
Gurung, Vinita   +5 more
core   +1 more source

Orthotopic liver transplantation in children. Two-year experience with 47 patients [PDF]

open access: yes, 1984
During a 24-month period (May 1981 to May 1983), 47 pediatric patients (ranging in age from 7 months to 18 years) underwent orthotopic liver transplantation using cyclosporine and prednisone.
Gartner, JC   +5 more
core  

The bile salt export pump [PDF]

open access: yes, 2018
Canalicular secretion of bile salts mediated by the bile salt export pump Bsep constitutes the major driving force for the generation of bile flow.
Meier, Peter   +2 more
core  

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