Results 1 to 10 of about 816 (152)

In silico repurposing of antipsychotic drugs for Alzheimer’s disease [PDF]

open access: yesBMC Neuroscience, 2017
Background Alzheimer’s disease (AD) is the most prevalent form of dementia and represents one of the highest unmet requirements in medicine today. There is shortage of novel molecules entering into market because of poor pharmacokinetic properties and ...
Shivani Kumar   +2 more
doaj   +2 more sources

Metalloproteinase-9 as a Pyroptosis-Hypoxia Synergy Effector Drives Immune Remodeling in Ischemic Stroke: A Multi-Omics Validated Diagnostic Biomarker and Therapeutic Target [PDF]

open access: yesInternational Journal of General Medicine
Jun Wu,* Da Wu,* Ming Qi, Kuan Jiang Department of Neurosurgery, Yixing People’s Hospital, Yixing, Jiangsu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Kuan Jiang, Department of ...
Wu J, Wu D, Qi M, Jiang K
doaj   +2 more sources

Insulin, Central Dopamine D2 Receptors, and Monetary Reward Discounting in Obesity. [PDF]

open access: yesPLoS ONE, 2015
Animal research finds that insulin regulates dopamine signaling and reward behavior, but similar research in humans is lacking. We investigated whether individual differences in body mass index, percent body fat, pancreatic β-cell function, and dopamine ...
Sarah A Eisenstein   +9 more
doaj   +1 more source

Pharmacological Treatment for Pedophilic Disorder and Compulsive Sexual Behavior Disorder: A Review. [PDF]

open access: yesDrugs, 2022
Landgren V   +6 more
europepmc   +1 more source

Principal Component Analysis of Striatal and Extrastriatal D2 Dopamine Receptor Positron Emission Tomography in Manganese-Exposed Workers. [PDF]

open access: yesToxicol Sci, 2021
Criswell SR   +9 more
europepmc   +1 more source

Leveraging nonstructural data to predict structures and affinities of protein-ligand complexes. [PDF]

open access: yesProc Natl Acad Sci U S A, 2021
Paggi JM   +10 more
europepmc   +1 more source

Erratum to: Radiation dosimetry of N-([11C]methyl)benperidol as determined by whole-body PET imaging of primates [PDF]

open access: bronze, 2013
Jo Ann V. Antenor‐Dorsey   +4 more
openalex   +1 more source

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