Results 111 to 120 of about 1,010 (187)
Insulin, Central Dopamine D2 Receptors, and Monetary Reward Discounting in Obesity [PDF]
, 2013 Gredysa, Danuta M.
core +1 more source
Modeling PET Data Acquired During Nonsteady Conditions: What If Brain Conditions Change During the Scan? [PDF]
J Nucl MedMorris ED +3 more
europepmc +1 more source
Why Do Chemically Similar Pharmaceutical Molecules Crystallize in Different Structures: A Case of Droperidol and Benperidol [PDF]
Crystal Growth & Design, 2016 A detailed study of molecular conformation and intermolecular interactions in the experimental crystal structures and general trends observed in the Cambridge Structural Database as well as theoretical calculations were performed to identify the reason for the formation of different crystal structures of two chemically very similar pharmaceutical ...
A. Be̅rziṇš, A. Actiņš
semanticscholar +3 more sources
Nuclear Medicine and Biology, 1997 Radiation absorbed doses due to IV administration of [18F](N-methyl) benperidol ([18F]NMB) were estimated by whole-body PET imaging of nonhuman primates. Time-activity curves were obtained for nine compartments (striatum, eyes, heart, lungs, liver, gallbladder, intestines, kidneys, bladder) by using dynamic PET scans of three different baboons given ...
S. Moerlein +3 more
semanticscholar +5 more sources
The Analyst, 1986 Benperidol contains two chromophores separated by a non-conjugated system. Its ultraviolet absorption spectrum, in acidic or neutral aqueous solution, shows maxima due to the p-fluoroacetophenone chromophore (at 249 nm) and to the benzimidazolone chromophore (at 232 and 279 nm).
A. Gassim, P. Takla, K. James
semanticscholar +5 more sources
Polymorphism and possible intramolecular bonding in benperidol
International Journal of Pharmaceutics, 1986 Abstract The existence of two polymorphs and two solvates of benperidol has been confirmed by IR spectrophotometry and differential scanning calorimetry, but an amorphous form and a possible third polymorph have been shown to be mixtures of the other two polymorphs.
A. Gassim, P. G. Takia, K. James
semanticscholar +4 more sources
Archives of Sexual Behavior, 1974 A method for assessing the effect of drugs on sexual drive and arousability has been developed and used to compare the effect of a butyrephenone, benperidol, with chlorpromazine and placebo. Measures of change used included sexual behavior ratings, self-ratings of frequency of sexual thoughts, semantic differential ratings, and penile erections to ...
G. Tennent, J. Bancroft, James Cass
semanticscholar +5 more sources
Benperidol - a drug for sexual offenders?
Drug and Therapeutics Bulletin, 1974 Benperidol (Anquil - Janssen) is a butyrophenone which the makers claim ‘removes the desire to indulge in antisocial forms of sexual behaviour but the ability to function appropriately in the normal sexual environment may be retained’. It is structurally similar to haloperidol (Serenace - Searle) and trifluperidol (Triperidol - Janssen), both of which ...
semanticscholar +3 more sources
Radiosynthesis of (N-[11C]methyl)benperidol for PET investigation of D2 receptor binding
Radiochimica Acta, 2004 Abstract A procedure for the reliable production of the novel PET D2 receptor ligand (N-[11C]methyl)benperidol ([11C]NMB) is described. The method is based on N-methylation of benperidol using [11C]methyl iodide from the PETtrace MeI MicroLab, with product purification via normal-phase HPLC.
S. Moerlein, J. Perlmutter, M. Welch
semanticscholar +4 more sources