Results 11 to 20 of about 816 (152)

Risk of Mortality (Including Sudden Cardiac Death) and Major Cardiovascular Events in Atypical and Typical Antipsychotic Users: A Study with the General Practice Research Database [PDF]

Cardiovascular Psychiatry and Neurology, Volume 2013, Issue 1, 2013., 2013
Objective. Antipsychotics have been associated with increased cardiac events including mortality. This study assessed cardiac events including mortality among antipsychotic users relative to nonusers. Methods. The General Practice Research Database (GPRD) was used to identify antipsychotic users, matched general population controls, and psychiatric ...
Tarita Murray-Thomas, Meghan E. Jones, Deven Patel, Elizabeth Brunner, Chetan C. Shatapathy, Stephen Motsko, Tjeerd P. Van Staa, Dominique L. Musselman   +7 more
wiley   +5 more sources

Effects of bariatric surgery and dietary interventions for obesity on brain neurotransmitter systems and metabolism: A systematic review of positron emission tomography (PET) and single‐photon emission computed tomography (SPECT) studies

Obesity Reviews, Volume 24, Issue 11, November 2023., 2023
Summary This systematic review collates studies of dietary or bariatric surgery interventions for obesity using positron emission tomography and single‐photon emission computed tomography. Of 604 publications identified, 22 met inclusion criteria. Twelve studies assessed bariatric surgery (seven gastric bypass, five gastric bypass/sleeve gastrectomy ...
Alhanouf S. Al‐Alsheikh, Shahd Alabdulkader, Alexander D. Miras, Anthony P. Goldstone   +3 more
wiley   +1 more source

A case series of serious and unexpected adverse drug reactions under treatment with cariprazine

Clinical Case Reports, Volume 9, Issue 5, May 2021., 2021
Reporting of new or unexpected adverse drug reactions of medicines that are subject to additional monitoring (“black triangle” label), such as the antipsychotic drug cariprazine, is of paramount importance to improve pharmacotherapy safety. Abstract Reporting of new or unexpected adverse drug reactions of medicines that are subject to additional ...
Johannes Heck, Johanna Seifert, Dirk O. Stichtenoth, Christoph Schroeder, Adrian Groh, Gregor R. Szycik, Detlef Degner, Ivana Adamovic, Michael Schneider, Catherine Glocker, Eckart Rüther, Stefan Bleich, Renate Grohmann, Sermin Toto   +13 more
wiley   +1 more source

Altered third‐party punishment in Huntington's disease: A study using neuroeconomic games

Brain and Behavior, Volume 11, Issue 1, January 2021., 2021
Huntington's disease (HD) is a heritable degenerative brain disease associated with a broad spectrum of neurocognitive dysfunction. Here, we studied patients' understanding of rules of social exchange using neuroeconomic games that required an understanding of unfairness.
Martin Brüne, Sarah Maria von Hein, Christian Claassen, Rainer Hoffmann, Carsten Saft   +4 more
wiley   +1 more source

A Study to Decipher the Potential Effects of Butylphthalide against Central Nervous System Diseases Based on Network Pharmacology and Molecular Docking Integration Strategy

Evidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021
Background. Butylphthalide (NBP), approved by the China National Medical Products Administration (NMPA) for the treatment of ischemic stroke (IS), showed pleiotropic potentials against central nervous system (CNS) diseases, including neuroprotection and cognitive deficits improvement.
Qinqin Zhao, Bei Zheng, Pinpin Feng, Xiang Li, Woon-Man Kung   +4 more
wiley   +1 more source

Radiation dosimetry of [F]VAT in nonhuman primates [PDF]

, 2015
BACKGROUND: The objective of this study is to determine the radiation dosimetry of a novel radiotracer for vesicular acetylcholine transporter (−)-(1-((2R,3R)-8-(2-[(18)F]fluoro-ethoxy)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)piperidin-4-yl)(4 ...
Jin, Hongjun, Karimi, Morvarid, Laforest, Richard, Perlmutter, Joel S, Tu, Zhude, Yue, Xuyi, Zhang, Xiang   +6 more
core   +5 more sources

Spatial reorganization of putaminal dopamine D2-like receptors in cranial and hand dystonia [PDF]

, 2013
The putamen has a somatotopic organization of neurons identified by correspondence of firing rates with selected body part movements, as well as by complex, but organized, differential cortical projections onto putamen.
Black, Kevin J, Mink, Jonathan W, Moerlein, Stephen M, Perlmutter, Joel S, Revilla, Fredy J, Snyder, Abraham Z, Tolia, Veeral N   +6 more
core   +7 more sources

Toxicity prediction of anti tuberculosis active molecules [PDF]

, 2011
The aim of the work was to understand the toxicity, physically significant descriptors and pharmaceutically relevant properties of some imidazoles obtained from the open sources that may found to be active against tuberculosis.
Abdul Jaleel.U.C, Sajeev R
core   +2 more sources

Emotional eating phenotype is associated with central dopamine D2 receptor binding independent of body mass index [PDF]

, 2015
PET studies have provided mixed evidence regarding central D2/D3 dopamine receptor binding and its relationship with obesity as measured by body mass index (BMI). Other aspects of obesity may be more tightly coupled to the dopaminergic system.
Al-Lozi, Amal, Antenor-Dorsey, Jo Ann V, Bischoff, Allison N, Black, Kevin J, Eisenstein, Sarah A, Gradysa, Danuta M, Hershey, Tamara, Klein, Samuel, Koller, Jonathan M, Morelein, Stephen M, Pepino, Marta Y, Perlmutter, Joel S   +11 more
core   +3 more sources

Reduction or discontinuation of antipsychotics for challenging behaviour in adults with intellectual disability: a systematic review [PDF]

, 2017
The use of antipsychotics to manage challenging behaviour in adults with intellectual disability is widespread but controversial, and evidence is scarce.
Hassiotis, A, Sheehan, R
core   +1 more source