Benperidol for schizophrenia. [PDF]
Cochrane Database of Systematic Reviews, 2005 Benperidol is a relatively old antipsychotic drug, marketed since 1966, used in Germany for 30 years, but also available in Belgium, Greece, Italy, the Netherlands and the UK. Benperidol is a butyrophenone antipsychotic, with the highest neuroleptic potency in terms of D2 receptor blockade.
S. Leucht, B. Hartung
semanticscholar +8 more sources
Acta Crystallographica Section A Foundations and Advances, 2023 We present an experimental and computational study of solid solution formation between structurally highly similar active pharmaceutical ingredients droperidol and benperidol in nonsolvates, dihydrates, and several solvates formed by these compounds. We demonstrate that the formation of solid solutions strongly depends on the crystal structure of the ...
K. Saršu̅ns, A. Be̅rziṇš
semanticscholar +4 more sources
Radiation dosimetry of N-([11C]methyl)benperidol as determined by whole-body PET imaging of primates [PDF]
European Journal of Nuclear Medicine and Molecular Imaging, 2008 N-([(11)C]methyl)benperidol ([(11)C]NMB) can be used for positron emission tomography (PET) measurements of D(2)-like dopamine receptor binding in vivo. We report the absorbed radiation dosimetry of i.v.-administered (11)C-NMB, a critical step before applying this radioligand to imaging studies in humans.Whole-body PET imaging with a CTI/Siemens ECAT ...
Joann V Antenor-Dorsey +4 more
semanticscholar +6 more sources
Computional studies of droperidol/benperidol solid-solution phase formation [PDF]
Acta Crystallographica Section A Foundations and Advances, 2018 E. Sala, A. Be̅rziṇš, K. Saršu̅ns
semanticscholar +3 more sources
In silico repurposing of antipsychotic drugs for Alzheimer’s disease [PDF]
BMC Neuroscience, 2017 Background Alzheimer’s disease (AD) is the most prevalent form of dementia and represents one of the highest unmet requirements in medicine today. There is shortage of novel molecules entering into market because of poor pharmacokinetic properties and ...
Shivani Kumar +2 more
doaj +2 more sources
An umbrella review of adverse effects associated with antipsychotic medications: the need for complementary study designs [PDF]
Neurosci Biobehav Rev, 2023 Antipsychotic medications are widely prescribed in psychotic illnesses and other mental disorders. Effectiveness is well-established, particularly for reducing symptoms such as delusions and hallucinations, but can be impacted by tolerability.
Chow R +5 more
europepmc +3 more sources
Risk of Mortality (Including Sudden Cardiac Death) and Major Cardiovascular Events in Atypical and Typical Antipsychotic Users: A Study with the General Practice Research Database [PDF]
Cardiovascular Psychiatry and Neurology, Volume 2013, Issue 1, 2013., 2013 Objective. Antipsychotics have been associated with increased cardiac events including mortality. This study assessed cardiac events including mortality among antipsychotic users relative to nonusers. Methods. The General Practice Research Database (GPRD) was used to identify antipsychotic users, matched general population controls, and psychiatric ...
Tarita Murray-Thomas +7 more
wiley +5 more sources
A comparison of D2 receptor specific binding in obese and normal‐weight individuals using PET with (N‐[11C]methyl)benperidol [PDF]
Synapse, 2013 S. Eisenstein +11 more
semanticscholar +2 more sources
Characterization of extrastriatal D2 in vivo specific binding of [18F](N‐methyl)benperidol using PET [PDF]
Synapse, 2012 S. Eisenstein +11 more
semanticscholar +2 more sources
Erratum to: Radiation dosimetry of N-([11C]methyl)benperidol as determined by whole-body PET imaging of primates [PDF]
European Journal of Nuclear Medicine and Molecular Imaging, 2013 Joann V Antenor-Dorsey +4 more
semanticscholar +2 more sources