Validation of the reference tissue model for estimation of dopaminergic D2-like receptor binding with [18F](N-methyl)benperidol in humans. [PDF]
Joann V Antenor-Dorsey+4 more
semanticscholar +2 more sources
Quantification of D2 Receptor Binding in the Rat Striatum Using SmallAnimal PET – The Impact of the Reference Tissue on the BindingPotential of [18F]N-Methyl-Benperidol [PDF]
S. Nikolaus+6 more
semanticscholar +2 more sources
Summary This systematic review collates studies of dietary or bariatric surgery interventions for obesity using positron emission tomography and single‐photon emission computed tomography. Of 604 publications identified, 22 met inclusion criteria. Twelve studies assessed bariatric surgery (seven gastric bypass, five gastric bypass/sleeve gastrectomy ...
Alhanouf S. Al‐Alsheikh+3 more
wiley +1 more source
Insulin, Central Dopamine D2 Receptors, and Monetary Reward Discounting in Obesity. [PDF]
Animal research finds that insulin regulates dopamine signaling and reward behavior, but similar research in humans is lacking. We investigated whether individual differences in body mass index, percent body fat, pancreatic β-cell function, and dopamine ...
Sarah A Eisenstein+9 more
doaj +1 more source
A case series of serious and unexpected adverse drug reactions under treatment with cariprazine
Reporting of new or unexpected adverse drug reactions of medicines that are subject to additional monitoring (“black triangle” label), such as the antipsychotic drug cariprazine, is of paramount importance to improve pharmacotherapy safety. Abstract Reporting of new or unexpected adverse drug reactions of medicines that are subject to additional ...
Johannes Heck+13 more
wiley +1 more source
Altered third‐party punishment in Huntington's disease: A study using neuroeconomic games
Huntington's disease (HD) is a heritable degenerative brain disease associated with a broad spectrum of neurocognitive dysfunction. Here, we studied patients' understanding of rules of social exchange using neuroeconomic games that required an understanding of unfairness.
Martin Brüne+4 more
wiley +1 more source
Background. Butylphthalide (NBP), approved by the China National Medical Products Administration (NMPA) for the treatment of ischemic stroke (IS), showed pleiotropic potentials against central nervous system (CNS) diseases, including neuroprotection and cognitive deficits improvement.
Qinqin Zhao+4 more
wiley +1 more source
Radiation dosimetry of [F]VAT in nonhuman primates [PDF]
BACKGROUND: The objective of this study is to determine the radiation dosimetry of a novel radiotracer for vesicular acetylcholine transporter (−)-(1-((2R,3R)-8-(2-[(18)F]fluoro-ethoxy)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)piperidin-4-yl)(4 ...
Jin, Hongjun+6 more
core +5 more sources
Spatial reorganization of putaminal dopamine D2-like receptors in cranial and hand dystonia [PDF]
The putamen has a somatotopic organization of neurons identified by correspondence of firing rates with selected body part movements, as well as by complex, but organized, differential cortical projections onto putamen.
Black, Kevin J+6 more
core +7 more sources
Emotional eating phenotype is associated with central dopamine D2 receptor binding independent of body mass index [PDF]
PET studies have provided mixed evidence regarding central D2/D3 dopamine receptor binding and its relationship with obesity as measured by body mass index (BMI). Other aspects of obesity may be more tightly coupled to the dopaminergic system.
Al-Lozi, Amal+11 more
core +3 more sources