Results 21 to 30 of about 816 (152)
Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation [PDF]
, 2010 A major obstacle for the discovery of psychoactive drugs is the inability to predict how small molecules will alter complex behaviors. We report the development and application of a high-throughput, quantitative screen for drugs that alter the behavior ...
Arvanites, Anthony +10 more
core +1 more source
Recent Advances in Imaging of Dopaminergic Neurons for Evaluation of Neuropsychiatric Disorders
BioMed Research International, Volume 2012, Issue 1, 2012., 2012 Dopamine is the most intensely studied monoaminergic neurotransmitter. Dopaminergic neurotransmission plays an important role in regulating several aspects of basic brain function, including motor, behavior, motivation, and working memory. To date, there are numerous positron emission tomography (PET) and single photon emission computed tomography ...
Lie-Hang Shen +3 more
wiley +1 more source
The Role of Molecular Imaging in the Diagnosis and Management of Neuropsychiatric Disorders
BioMed Research International, Volume 2011, Issue 1, 2011., 2011 Neuropsychiatric disorders are becoming a major socioeconomic burden to modern society. In recent years, a dramatic expansion of tools has facilitated the study of the molecular basis of neuropsychiatric disorders. Molecular imaging has enabled the noninvasive characterization and quantification of biological processes at the cellular, tissue, and ...
Lie-Hang Shen +4 more
wiley +1 more source
Interventions for Learning Disabled Sex Offenders
Campbell Systematic Reviews, Volume 1, Issue 1, Page 1-26, 2005., 2005 The aim of this Campbell systematic review is to assess the efficacy of interventions with learning disabled sex offenders. Sex offending is of increasing public concern with calls for longer terms of imprisonment and closer supervision of such offenders in the community.
Lorraine Ashman, Lorna Duggan
wiley +1 more source
Withdrawal versus continuation of long-term antipsychotic drug use for behavioural and psychological symptoms in older people with dementia [PDF]
, 2018 Background : Antipsychotic agents are often used to treat neuropsychiatric symptoms (NPS) in people with dementia although there is uncertainty about the effectiveness of their long-term use for this indication and concern that they may cause harm ...
Christiaens, Thierry +6 more
core +2 more sources
Biological Reviews, Volume 100, Issue 5, Page 1994-2019, October 2025.ABSTRACT Antipsychotic drugs (APDs) are a diverse class of neuroactive pharmaceuticals increasingly detected in surface and ground waters globally. Some APDs are classified as posing a high environmental risk, due, in part, to their tendency to bioaccumulate in wildlife, including fish.
Gabrielle Wasser‐Bennett +4 more
wiley +1 more source
Absorbed radiation dosimetry of the D3-specific PET radioligand [18F]FluorTriopride estimated using rodent and nonhuman primate [PDF]
, 2016 [(18)F]FluorTriopride ([(18)F]FTP) is a dopamine D(3)-receptor preferring radioligand with potential for investigation of neuropsychiatric disorders including Parkinson disease, dystonia and schizophrenia. Here we estimate human radiation dosimetry for [(
Bognar, Christopher +9 more
core +1 more source
Duplications in RB1CC1 are associated with schizophrenia; identification in large European sample sets [PDF]
, 2013 Schizophrenia (SCZ) is a severe and debilitating neuropsychiatric disorder with an estimated heritability of ~80%. Recently, de novo mutations, identified by next-generation sequencing (NGS) technology, have been suggested to contribute to the risk of ...
A Corvin +39 more
core +3 more sources
Focal Spot, Fall/Winter 1993 [PDF]
, 1993 https://digitalcommons.wustl.edu/focal_spot_archives/1065/thumbnail ...
core +1 more source