Toxicity prediction of anti tuberculosis active molecules [PDF]
, 2011 The aim of the work was to understand the toxicity, physically significant descriptors and pharmaceutically relevant properties of some imidazoles obtained from the open sources that may found to be active against tuberculosis.
Abdul Jaleel.U.C, Sajeev R
core +2 more sources
Reduction or discontinuation of antipsychotics for challenging behaviour in adults with intellectual disability: a systematic review [PDF]
, 2017 The use of antipsychotics to manage challenging behaviour in adults with intellectual disability is widespread but controversial, and evidence is scarce.
Hassiotis, A, Sheehan, R
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Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation [PDF]
, 2010 A major obstacle for the discovery of psychoactive drugs is the inability to predict how small molecules will alter complex behaviors. We report the development and application of a high-throughput, quantitative screen for drugs that alter the behavior ...
Arvanites, Anthony +10 more
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Recent Advances in Imaging of Dopaminergic Neurons for Evaluation of Neuropsychiatric Disorders
BioMed Research International, Volume 2012, Issue 1, 2012., 2012 Dopamine is the most intensely studied monoaminergic neurotransmitter. Dopaminergic neurotransmission plays an important role in regulating several aspects of basic brain function, including motor, behavior, motivation, and working memory. To date, there are numerous positron emission tomography (PET) and single photon emission computed tomography ...
Lie-Hang Shen +3 more
wiley +1 more source
The Role of Molecular Imaging in the Diagnosis and Management of Neuropsychiatric Disorders
BioMed Research International, Volume 2011, Issue 1, 2011., 2011 Neuropsychiatric disorders are becoming a major socioeconomic burden to modern society. In recent years, a dramatic expansion of tools has facilitated the study of the molecular basis of neuropsychiatric disorders. Molecular imaging has enabled the noninvasive characterization and quantification of biological processes at the cellular, tissue, and ...
Lie-Hang Shen +4 more
wiley +1 more source
Interventions for Learning Disabled Sex Offenders
Campbell Systematic Reviews, Volume 1, Issue 1, Page 1-26, 2005., 2005 The aim of this Campbell systematic review is to assess the efficacy of interventions with learning disabled sex offenders. Sex offending is of increasing public concern with calls for longer terms of imprisonment and closer supervision of such offenders in the community.
Lorraine Ashman, Lorna Duggan
wiley +1 more source
Antidepressant and antipsychotic drug prescribing and diabetes outcomes:a systematic review of observational studies [PDF]
, 2023 Aims: Psychotropic medication may be associated with adverse effects, including among people with diabetes. We conducted a systematic review of observational studies investigating the association between antidepressant or antipsychotic drug prescribing ...
Greene, Charlotte +6 more
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Withdrawal versus continuation of long-term antipsychotic drug use for behavioural and psychological symptoms in older people with dementia [PDF]
, 2018 Background : Antipsychotic agents are often used to treat neuropsychiatric symptoms (NPS) in people with dementia although there is uncertainty about the effectiveness of their long-term use for this indication and concern that they may cause harm ...
Christiaens, Thierry +6 more
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Experimental and computational investigation of benperidol and droperidol solid solutions in different crystal structures [PDF]
, 2022 Kristaps Saršu̅ns, Agris Bērziņš
openalex +3 more sources
Absorbed radiation dosimetry of the D3-specific PET radioligand [18F]FluorTriopride estimated using rodent and nonhuman primate [PDF]
, 2016 [(18)F]FluorTriopride ([(18)F]FTP) is a dopamine D(3)-receptor preferring radioligand with potential for investigation of neuropsychiatric disorders including Parkinson disease, dystonia and schizophrenia. Here we estimate human radiation dosimetry for [(
Bognar, Christopher +9 more
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