Asthma referrals : a key component of asthma management that needs to be addressed [PDF]
, 2017 Peer reviewedPublisher ...
Bergen, David A +3 more
core +1 more source
Dupilumab: A new paradigm for the treatment of allergic diseases [PDF]
, 2018 Moderate and severe forms of allergic diseases such as atopic dermatitis and asthma are a challenge for clinicians. In these conditions, which severely affect the quality of life of the patient and frequently have associated allergic comorbidities, the ...
Dávila, Ignacio, Sastre, Joaquín
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Respirology Case Reports, 2023 There is limited data on the use of benralizumab in patients with severe asthma, who have allergic bronchopulmonary aspergillosis (ABPA). We report the case of a 65‐year‐old woman with combined severe eosinophilic and allergic asthma, who presented with ...
Arvindran Alaga +2 more
doaj +1 more source
DP1 receptor signaling prevents the onset of intrinsic apoptosis in eosinophils and functions as a transcriptional modulator [PDF]
, 2018 Prostaglandin (PG) D2 is the ligand for the G‐protein coupled receptors DP1 (D‐type prostanoid receptor 1) and DP2 (also known as chemoattractant receptor homologous molecule, expressed on Th2 cells; CRTH2).
Heinemann, A. +9 more
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Group 2 Innate Lymphoid Cells in Respiratory Allergic Inflammation [PDF]
, 2019 Millions of people worldwide are suffering from allergic inflammatory airway disorders. These conditions are regarded as a consequence of multiple imbalanced immune events resulting in an inadequate response with the exact underlying mechanisms still ...
Duerr, Claudia U. +3 more
core +1 more source
ChAracterization of ItaliaN severe uncontrolled Asthmatic patieNts Key features when receiving Benralizumab in a real-life setting: the observational rEtrospective ANANKE study [PDF]
, 2022 Background: Data from phase 3 trials have demonstrated the efficacy and safety of benralizumab in patients with severe eosinophilic asthma (SEA). We conducted a real-world study examining the baseline characteristics of a large SEA population treated ...
Aliani, Maria +24 more
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Research highlights from the 2018 European Respiratory Society International Congress: Airway disease [PDF]
, 2010 The annual European Respiratory Society (ERS) International Congress (held in Paris in 2018) was once again a platform for discussion of the highest-quality scientific research, cutting-edge techniques and innovative new therapies within the respiratory ...
Andersson, Cecilia +6 more
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The role of benralizumab in eosinophilic immune dysfunctions: a case report-based literature review [PDF]
, 2023 In the past years, the knowledge of eosinophils playing a primary pathophysiologic role in several associated conditions has led to the development of biologics targeting therapies aiming at normalizing the immune response, reducing chronic inflammation,
Branco, Joana +5 more
core +1 more source
Omalizumab as alternative to chronic use of oral corticosteroids in severe asthma
, 2019 Systemic/oral corticosteroids (OCS) have been used for decades in the management of acute asthma exacerbations and chronically in patients with uncontrolled severe asthma.
Bousquet, Jean +6 more
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Arthritis &Rheumatology, Accepted Article.Background Eosinophilic granulomatosis with polyangiitis (EGPA) is a small vessel vasculitis characterized by eosinophilia, asthma, and ear, nose, throat (ENT) involvement. Although glucocorticoids (GCs) are effective in controlling symptoms, relapses and GC dependence are common.
Matthias Papo +35 more
wiley +1 more source