Results 91 to 100 of about 30,899 (241)

Indole‐Based π‐Extended Monophosphine Ligands for Enhanced Palladium‐Catalyzed Sonogashira Coupling

Journal of Heterocyclic Chemistry, EarlyView.
A general palladium‐catalyzed Sonogashira cross‐coupling of (hetero)aryl chlorides with aliphatic, (hetero)aryl alkynes is described using Pd(dba)₂/PCy2‐Napdole‐phos catalyst system. The reaction protocol exhibits broad substrate scope and the catalyst loading can be down to 0.2 mol% Pd.
Yu Kiu Lau, Chun Pong Hui, Cheuk Long Li, Ho Chung Chang, Man Ho Tse, Ho Kwan Lou, Iat In Chan, Raymond Wai‐Yin Sun, Pui Ying Choy, Fuk Yee Kwong   +9 more
wiley   +1 more source

Poly(O‐Propargyl‐N‐Amino Carbamate), a Reactive Polymer to Underpin Biomedical Applications of Poly(acetylene)s

Macromolecular Rapid Communications, EarlyView.
We report here a new methodology to prepare functional poly(acetylene)s under aqueous conditions. This methodology is underpinned by poly(O‐propargyl‐N‐amino carbamate) (P1), a reactive poly(acetylene) carrying acyl hydrazines. Thus, P1 reacts with aldehydes to give functional poly(acetylene)s, including cationic, hydrophobic, and sugar‐loaded poly ...
Tom Leigh, Greta Bellio, Daniel Crisan, Amit Deb, Alba Ramil‐Bouzas, Andrey Romanyuk, Ivan Torreiro‐Leon, Ana Rey‐Rico, Paco Fernandez‐Trillo   +8 more
wiley   +1 more source

Aliphatic Poly(Carbonate)s with Acid Responsive Release Mechanisms for Micellar Anti‐Tumor Drug Delivery

Macromolecular Rapid Communications, EarlyView.
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley   +1 more source

Generalist‐pollinated Arabis alpina exhibits floral scent variation at multiple scales

Nordic Journal of Botany, EarlyView.
Plants that depend on animals for reproduction often use complex floral traits to attract pollinators. Floral scent is recognized as part of the pollinator attraction module and can be shaped by plant‐pollinator interactions. In recent decades, research has started to reveal the dynamic properties of floral scent, identifying patterns of spatial and ...
Hanna Thosteman, Katherine Eisen, Clara McNaughton Montgomery, Xuefei Cheng, Loretta Pace, Magne Friberg   +5 more
wiley   +1 more source

FeCl3‐Catalyzed Synthesis of Ynones from Silylated Alkynes and Acetic Anhydride

ChemistryOpen, EarlyView.
The synthesis of alkynones from silylated alkynes and acid chlorides, first reported by Birkhofer in 1963, remains a valuable transformation. However, its reliance on stoichiometric AlCl3 and corrosive reagents raises environmental and practical concerns. To address this, a greener protocol using catalytic FeCl3 and acetic anhydride is developed.
Paul Charki, Urs Gellrich, Daniel S. Müller   +2 more
wiley   +1 more source

Microwave‐Assisted Organic Syntheses in Deep Eutectic Solvents: A Win‐Win Association for Sustainable Chemistry

ChemistryOpen, EarlyView.
In organic synthesis, deep eutectic solvents (DES) have demonstrated their ability to be used as reaction media for the development of reactions in line with green chemistry principles. This review presents an overview of microwave‐assisted organic synthesis in DES, highlighting the diversity of uses for these solvents, their role in mechanisms, the ...
Pierre‐Olivier Delaye, Chefikou Salami, Emilie Thiery   +2 more
wiley   +1 more source

Synthesis of Pyrido[2,3‐d]Azolopyrimidinones: Design and Epidermal Growth Factor Receptor‐Targeted Molecular Docking Toward Novel Anticancer Leads

ChemistryOpen, EarlyView.
New pyrido[2,3‐d]azolopyrimidinones were synthesized and evaluated as potent EGFR‐targeted anticancer leads. Molecular docking and cytotoxicity studies revealed strong receptor binding and submicromolar activity, highlighting this scaffold as a promising framework for future targeted drug development.
Sobhi M. Gomha, Sami A. Al‐Hussain, Basant Farag, AbdElAziz A. Nayl, Wesam Hussein, Abdelwahed R. Sayed, Magdi E. A. Zaki   +6 more
wiley   +1 more source

Dual‐Crosslinked Hydrogels With Enhanced Mechanical and Thermal Properties

Journal of Polymer Science, EarlyView.
An illustrative depiction of a dual‐crosslinked polymer network achieved with dynamic crosslinkers (blue) and covalent crosslinkers (red). ABSTRACT Creating artificial skin requires materials that can mimic the mechanical properties and structural integrity of natural skin.
Lilian Boton, Brett Leslie Pollard, Luke A. Connal   +2 more
wiley   +1 more source

Wheat fertilization affects oviposition preference of wheat midge, Sitodiplosis mosellana (Géhin) (Diptera: Cecidomyiidae)

Pest Management Science, EarlyView.
Wheat fertilization increased plant growth, nitrogen and protein levels, influencing the wheat volatile profile and affecting female wheat midge choice to lay eggs. This could partly result from the observed changes in the VOC profile. Abstract BACKGROUND In Canada, the orange wheat blossom midge (hereafter called wheat midge), Sitodiplosis mosellana ...
Chaminda De Silva Weeraddana, Ramya Wijesundara, Sheri A. Schmidt, A. Paulina de la Mata, Curt McCartney, James J. Harynuk, Alejandro C. Costamagna   +6 more
wiley   +1 more source

Enantiopurity‐Dependent Peptide Coacervates and Asymmetric Organocatalysis

Small, EarlyView.
Enantiopure peptide LLLPFF‐OCH3 forms liquid–liquid phase‐separated (LLPS) droplets that act as chiral microreactors for enantioselective aldol catalysis. Racemic mixtures fail to undergo LLPS, showing spontaneous enantiomeric self‐disproportionation (SDE).
Alice Vetrano, Nico di Fonte, Olivier Monasson, Federico Perrella, Martina Porco, Ferdinando Mercuri, Gianluca Dell'Orletta, Francesco Petragnano, Alessio Carioscia, Davide Deodato, Damiano Calcagno, Giovanna Salvitti, Samantha Reale, Fabio Pesciaioli, Carino Ferrante, Davide Tedeschi, Giuseppe Grasso, Paola Benassi, Elisa Peroni, Armando Carlone, Isabella Daidone, Claudio Iacobucci   +21 more
wiley   +1 more source