Results 121 to 130 of about 30,899 (241)
Targeting Expanded CUG and CTG Repeats as a Therapeutic Approach for Myotonic Dystrophy Type 1 (DM1)
DM1 is an RNA gain‐of‐function disease caused by CTG repeat expansion, producing toxic r(CUG)exp RNA that sequesters MBNL1 and impairs splicing. This review covers the field of CUG and CTG ligands identified or rationally designed as DM1 drug candidates, highlighting their molecular design, RNA‐ or DNA‐binding modes, in vitro affinities and ...
Camille Richagneux, Anton Granzhan
wiley +1 more source
Room temperature synthesis of α,β-unsaturated nitriles by manganese-catalysed base-free coupling of α-saturated nitriles with aldehydes. [PDF]
Thiyagarajan S +5 more
europepmc +1 more source
Gas-Phase Formation of Trioxy Acid via OH-Initiated Aldehyde Oxidation under Atmospheric Conditions. [PDF]
Ahongshangbam E +5 more
europepmc +1 more source
Die Implementierung von Kronenethern in den Liganden von Kobaltporphyrinen wirkt sich in mehrfacher Hinsicht positiv auf die elektrochemische CO2‐Reduktion aus: 1. Das Reduktionspotenzial wird in Gegenwart von K+ gesenkt; 2. die CO‐Erzeugung in Zero‐Gap‐Elektrolyseuren wird gesteigert und 3.
Wiebke Wiesner +7 more
wiley +1 more source
Automated Nanocrystalline Sponge Workflow Enabled by 3D Electron Diffraction. [PDF]
Butonova S +5 more
europepmc +1 more source
Bio-inspired asymmetric Zn-N<sub>2</sub>O<sub>2</sub> single-atom catalysts via natural skeleton for efficient N-alkylation of nitroarenes with alcohols. [PDF]
Huang Y +9 more
europepmc +1 more source
The implementation of crown ethers into the ligand of cobalt porphyrins benefits the electrochemical CO2 reduction in the several ways: (1) the reduction potential is lowered in presence of K+; (2) it boosts the CO generation in Zero‐Gap Electrolyzers and (3) ensures complex stability during electrolysis.
Wiebke Wiesner +7 more
wiley +1 more source
Coordination Polymers Assembled from Flexible Tricarboxylate Linkers: Hydrothermal Synthesis, Structural Diversity, and Catalytic Features. [PDF]
Dou W +5 more
europepmc +1 more source
One‐pot transition‐metal‐free methods for the synthesis of all three bonds of the alkyne's triple bond are reviewed. After analysis of several named reactions and discussion of improvements, recent advances in the synthesis of alkynes are discussed. Each section contains a proposed reaction mechanism and analysis of the strengths and weaknesses of the ...
Eugene Kim +4 more
wiley +1 more source

