Results 121 to 130 of about 30,899 (241)

Targeting Expanded CUG and CTG Repeats as a Therapeutic Approach for Myotonic Dystrophy Type 1 (DM1)

open access: yesChemMedChem, Volume 21, Issue 5, 13 March 2026.
DM1 is an RNA gain‐of‐function disease caused by CTG repeat expansion, producing toxic r(CUG)exp RNA that sequesters MBNL1 and impairs splicing. This review covers the field of CUG and CTG ligands identified or rationally designed as DM1 drug candidates, highlighting their molecular design, RNA‐ or DNA‐binding modes, in vitro affinities and ...
Camille Richagneux, Anton Granzhan
wiley   +1 more source

Gas-Phase Formation of Trioxy Acid via OH-Initiated Aldehyde Oxidation under Atmospheric Conditions. [PDF]

open access: yesJ Phys Chem Lett
Ahongshangbam E   +5 more
europepmc   +1 more source

Schwer wiegt die Krone: Kronenethermodulation von Kobaltporphyrinen in der CO2 Elektroreduktion in Zero‐Gap Electrolyseuren

open access: yesAngewandte Chemie, Volume 138, Issue 11, 9 March 2026.
Die Implementierung von Kronenethern in den Liganden von Kobaltporphyrinen wirkt sich in mehrfacher Hinsicht positiv auf die elektrochemische CO2‐Reduktion aus: 1. Das Reduktionspotenzial wird in Gegenwart von K+ gesenkt; 2. die CO‐Erzeugung in Zero‐Gap‐Elektrolyseuren wird gesteigert und 3.
Wiebke Wiesner   +7 more
wiley   +1 more source

Automated Nanocrystalline Sponge Workflow Enabled by 3D Electron Diffraction. [PDF]

open access: yesJ Am Chem Soc
Butonova S   +5 more
europepmc   +1 more source

Heavy is the Crown: Crown Ether Modulation of Cobalt Porphyrin CO2 Electroreduction in Zero‐Gap Electrolyzers

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 11, 9 March 2026.
The implementation of crown ethers into the ligand of cobalt porphyrins benefits the electrochemical CO2 reduction in the several ways: (1) the reduction potential is lowered in presence of K+; (2) it boosts the CO generation in Zero‐Gap Electrolyzers and (3) ensures complex stability during electrolysis.
Wiebke Wiesner   +7 more
wiley   +1 more source

One‐Pot Transition‐Metal‐Free Methods for the Synthesis of All Three Bonds of the Alkyne's Triple Bond

open access: yesChemistry – A European Journal, Volume 32, Issue 10, 9 March 2026.
One‐pot transition‐metal‐free methods for the synthesis of all three bonds of the alkyne's triple bond are reviewed. After analysis of several named reactions and discussion of improvements, recent advances in the synthesis of alkynes are discussed. Each section contains a proposed reaction mechanism and analysis of the strengths and weaknesses of the ...
Eugene Kim   +4 more
wiley   +1 more source

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